The expression of endothelin-1 in chronic lymphocytic leukemia is controlled by epigenetic mechanisms and extracellular stimuli.

Martinelli, Silvia; Maffei, Rossana; Fiorcari, Stefania; Quadrelli, Chiara; Zucchini, Patrizia; Benatti, Stefania; Potenza, Leonardo; Luppi, Mario; Marasca, Roberto

Martinelli, Silvia; Maffei, Rossana; Fiorcari, Stefania; Quadrelli, Chiara; Zucchini, Patrizia; Benatti, Stefania; Potenza, Leonardo; Luppi, Mario; Marasca, Roberto.

Afiliação

Martinelli S; Hematology Division, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Maffei R; Hematology Division, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Fiorcari S; Hematology Division, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Quadrelli C; Hematology Division, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Zucchini P; Hematology Division, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Benatti S; Hematology Division, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Potenza L; Hematology Division, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Luppi M; Hematology Division, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Marasca R; Hematology Division, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy. Electronic address: roberto.marasca@unimore.it.

Leuk Res ; 54: 17-24, 2017 03.

Article em En | MEDLINE | ID: mdl-28092772

Assuntos

Endotelina-1/genética; Epigênese Genética; Leucemia Linfocítica Crônica de Células B/metabolismo; Adulto; Idoso; Idoso de 80 Anos ou mais; Antígenos CD40/metabolismo; Metilação de DNA; Feminino; Expressão Gênica; Humanos; Leucemia Linfocítica Crônica de Células B/genética; Masculino; Pessoa de Meia-Idade; NF-kappa B/metabolismo; Transdução de Sinais; Receptores Toll-Like/metabolismo; Células Tumorais Cultivadas

Palavras-chave

CD40 stimulation; Chronic lymphocytic leukemia; DNA methylation; Endothelin-1; NF-kB; Transcriptional regulation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Endotelina-1 / Epigênese Genética Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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