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PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy.
Ruf, Stefanie; Heberle, Alexander Martin; Langelaar-Makkinje, Miriam; Gelino, Sara; Wilkinson, Deepti; Gerbeth, Carolin; Schwarz, Jennifer Jasmin; Holzwarth, Birgit; Warscheid, Bettina; Meisinger, Chris; van Vugt, Marcel A T M; Baumeister, Ralf; Hansen, Malene; Thedieck, Kathrin.
Afiliação
  • Ruf S; a Department of Bioinformatics and Molecular Genetics, Faculty of Biology , University of Freiburg , Freiburg , Germany.
  • Heberle AM; b Department of Pediatrics, Center for Liver, Digestive and Metabolic Diseases , University of Groningen, University Medical Center Groningen , AV Groningen , The Netherlands.
  • Langelaar-Makkinje M; c BIOSS Centre for Biological Signalling Studies , University of Freiburg , Freiburg , Germany.
  • Gelino S; d Research Training Group (RTG) 1104 , University of Freiburg , Freiburg , Germany.
  • Wilkinson D; b Department of Pediatrics, Center for Liver, Digestive and Metabolic Diseases , University of Groningen, University Medical Center Groningen , AV Groningen , The Netherlands.
  • Gerbeth C; b Department of Pediatrics, Center for Liver, Digestive and Metabolic Diseases , University of Groningen, University Medical Center Groningen , AV Groningen , The Netherlands.
  • Schwarz JJ; e Program of Development, Aging and Regeneration , Sanford Burnham Prebys Medical Discovery Institute , La Jolla , CA , USA.
  • Holzwarth B; f Graduate School of Biomedical Sciences , Sanford Burnham Prebys Medical Discovery Institute , La Jolla , CA , USA.
  • Warscheid B; e Program of Development, Aging and Regeneration , Sanford Burnham Prebys Medical Discovery Institute , La Jolla , CA , USA.
  • Meisinger C; c BIOSS Centre for Biological Signalling Studies , University of Freiburg , Freiburg , Germany.
  • van Vugt MA; g ZBMZ Centre for Biochemistry and Molecular Cell Research (Faculty of Medicine) , University of Freiburg , Freiburg , Germany.
  • Baumeister R; h Institute of Biochemistry and Molecular Biology (Faculty of Medicine), University of Freiburg , Freiburg , Germany.
  • Hansen M; i Department of Biochemistry and Functional Proteomics, Faculty of Biology , University of Freiburg , Freiburg , Germany.
  • Thedieck K; j Spemann Graduate School of Biology and Medicine (SGBM) , University of Freiburg , Freiburg , Germany.
Autophagy ; 13(3): 486-505, 2017 Mar 04.
Article em En | MEDLINE | ID: mdl-28102733
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Proteínas Proto-Oncogênicas / Proteínas Serina-Treonina Quinases / Proteínas de Ciclo Celular / Proteínas de Caenorhabditis elegans / Alvo Mecanístico do Complexo 1 de Rapamicina Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Proteínas Proto-Oncogênicas / Proteínas Serina-Treonina Quinases / Proteínas de Ciclo Celular / Proteínas de Caenorhabditis elegans / Alvo Mecanístico do Complexo 1 de Rapamicina Idioma: En Ano de publicação: 2017 Tipo de documento: Article