Polyporus squamosus Lectin 1a (PSL1a) Exhibits Cytotoxicity in Mammalian Cells by Disruption of Focal Adhesions, Inhibition of Protein Synthesis and Induction of Apoptosis.

Manna, Dipankar; Pust, Sascha; Torgersen, Maria L; Cordara, Gabriele; Künzler, Markus; Krengel, Ute; Sandvig, Kirsten

Manna, Dipankar; Pust, Sascha; Torgersen, Maria L; Cordara, Gabriele; Künzler, Markus; Krengel, Ute; Sandvig, Kirsten.

Afiliação

Manna D; Department of Chemistry, University of Oslo, Oslo, Norway.
Pust S; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
Torgersen ML; Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Cordara G; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
Künzler M; Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Krengel U; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
Sandvig K; Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway.

PLoS One ; 12(1): e0170716, 2017.

Article em En | MEDLINE | ID: mdl-28114329

Assuntos

Apoptose/efeitos dos fármacos; Adesões Focais/efeitos dos fármacos; Lectinas/farmacologia; Polyporus/metabolismo; Inibidores da Síntese de Proteínas/farmacologia; Autofagia/efeitos dos fármacos; Linhagem Celular Tumoral; Meios de Cultura; Replicação do DNA/efeitos dos fármacos; Adesões Focais/metabolismo; Humanos; Proteólise

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Síntese de Proteínas / Apoptose / Adesões Focais / Polyporus / Lectinas Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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