Pomalidomide experience: an effective therapeutic approach with immunomodulatory drugs in a patient with relapsed-refractory multiple myeloma.
Future Oncol
; 13(5s): 3-6, 2017 Feb.
Article
em En
| MEDLINE
| ID: mdl-28116941
ABSTRACT
Here we discuss the case of a heavily pretreated male patient with relapsed-refractory multiple myeloma and previous monoclonal gammopathy of undetermined significance who initiated a fifth-line treatment with pomalidomide (4 mg orally, days 1-21 of a 28-day cycle) and low-dose dexamethasone (40 mg weekly orally). A total of 3 months later, very good partial response was achieved and complete response was maintained for 7 months. This case illustrates the field-practice experience on the benefits of pomalidomide in a relapsed-refractory multiple myeloma patient with a previous history of monoclonal gammopathy of undetermined significance. Indeed, the pomalidomide/dexamethasone regimen resulted in a longer progression-free survival compared with previous regimens and demonstrated a good long-term tolerability.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Talidomida
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Fatores Imunológicos
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Mieloma Múltiplo
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Antineoplásicos
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article