Palladium-catalyzed carbonylative synthesis of isocoumarins and phthalides by using phenyl formate as a carbon monoxide source.
Org Biomol Chem
; 15(7): 1628-1635, 2017 Feb 21.
Article
em En
| MEDLINE
| ID: mdl-28120978
ABSTRACT
A simple and efficient palladium-catalyzed intramolecular carbonylative synthesis of isocoumarins and phthalides from the easily available starting materials by employing phenyl formate as a CO surrogate has been achieved. The approach affords target compounds in good to excellent yields with the advantages of lower toxicity, milder conditions, easy operation and wide functional group tolerance.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Paládio
/
Benzofuranos
/
Monóxido de Carbono
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Isocumarinas
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Formiatos
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article