Intraocular Dexamethasone Implant as Adjunct to Silicone Oil Tamponade for Proliferative Vitreoretinopathy.
Klin Monbl Augenheilkd
; 234(4): 501-504, 2017 Apr.
Article
em En
| MEDLINE
| ID: mdl-28147403
ABSTRACT
Background Proliferative vitreoretinopathy (PVR) occurs in 10â% of patients with retinal detachment and is characterized by excessive epi-, sub- or intraretinal contraction. Corticosteroids have been shown to counter this contraction. Patients and Methods Retrospective review of 5 patients (3 females, 2 males) with recurrent retinal detachment with stage C PVR. The mean age was 61.2 ± 20.5 years and myopia > - 5.0 dioptres was present in 3 eyes. Patients were treated with 23 g vitrectomy, retinectomy and endolaser, dexamethasone (Ozurdex®) injection under perfluorocarbone and 5500 cs silicone oil tamponade. Results After a total follow-up of 8.8 ± 6.4 months with silicone oil tamponade, the Ozurdex® implant was localised in the macula in 1 case, and in 4 cases behind the iris with a completely attached retina. Preoperative intraocular pressure was 11.0 ± 4.0 mmHg, which remained stable at 7.8 ± 3.5 mmHg at the end of the final follow-up. No localised adverse effects were observed of the implant on the retina or the iris. Conclusions The dexamethasone implant Ozurdex® is well tolerated in conjunction with silicone oil tamponade in eyes with retinal detachment and PVR. The implant may be a potential candidate for the prevention of PVR.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Óleos de Silicone
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Dexametasona
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Vitreorretinopatia Proliferativa
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Implantes de Medicamento
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Tamponamento Interno
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article