En-Bloc Transplant of the Liver, Kidney and Pancreas: Experience from a Latin American Transplant Center.
Am J Case Rep
; 18: 114-118, 2017 Feb 02.
Article
em En
| MEDLINE
| ID: mdl-28148909
ABSTRACT
BACKGROUND En-bloc transplantation is a surgical procedure in which multiple organs are transplanted simultaneously. It has some similarities with multi-organ transplantation but offers certain advantages. This report highlights the experience of our interdisciplinary group regarding the treatment and follow-up of patients who received en-bloc transplantation, with the aim of encouraging the development of this surgical technique. CASE REPORT The first case is a 38-year-old patient with type 1 diabetes mellitus, liver cirrhosis, and chronic kidney failure who received an en-bloc transplant of the liver, pancreas, and kidney with no intraoperative complications. He had a prolonged hospital stay due to anemia and systemic inflammatory response syndrome, which were resolved successfully. At follow-up, he had no requirement for insulin or for dialysis, or for new interventions. The second case describes a 48-year-old patient with type 2 diabetes mellitus, renal failure, and liver cirrhosis who received an en-bloc transplant of the liver, pancreas, and kidney with no complications. During the postoperative period, the patient suffered a possible episode of acute tubular necrosis, which evolved towards improvement, with a tendency to normal metabolic and renal functioning, with no additional events. The patient is currently in follow-up and is insulin-independent. CONCLUSIONS En-bloc transplantation is a safe procedure, which is technically simple and which achieves excellent results. This procedure is indicated in patients with end-stage renal disease, cirrhosis, and diabetes mellitus that is difficult to control.
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Base de dados:
MEDLINE
Assunto principal:
Transplante de Rim
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Transplante de Fígado
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Transplante de Pâncreas
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Diabetes Mellitus Tipo 1
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Diabetes Mellitus Tipo 2
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Falência Renal Crônica
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Cirrose Hepática
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article