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A Comparative Analysis of Drug-Induced Hepatotoxicity in Clinically Relevant Situations.
Thiel, Christoph; Cordes, Henrik; Fabbri, Lorenzo; Aschmann, Hélène Eloise; Baier, Vanessa; Smit, Ines; Atkinson, Francis; Blank, Lars Mathias; Kuepfer, Lars.
Afiliação
  • Thiel C; Institute of Applied Microbiology (iAMB), Aachen Biology and Biotechnology (ABBt), RWTH Aachen University, Worringerweg 1, Aachen, Germany.
  • Cordes H; Institute of Applied Microbiology (iAMB), Aachen Biology and Biotechnology (ABBt), RWTH Aachen University, Worringerweg 1, Aachen, Germany.
  • Fabbri L; Institute of Applied Microbiology (iAMB), Aachen Biology and Biotechnology (ABBt), RWTH Aachen University, Worringerweg 1, Aachen, Germany.
  • Aschmann HE; Institute of Applied Microbiology (iAMB), Aachen Biology and Biotechnology (ABBt), RWTH Aachen University, Worringerweg 1, Aachen, Germany.
  • Baier V; Institute of Applied Microbiology (iAMB), Aachen Biology and Biotechnology (ABBt), RWTH Aachen University, Worringerweg 1, Aachen, Germany.
  • Smit I; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.
  • Atkinson F; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.
  • Blank LM; Institute of Applied Microbiology (iAMB), Aachen Biology and Biotechnology (ABBt), RWTH Aachen University, Worringerweg 1, Aachen, Germany.
  • Kuepfer L; Institute of Applied Microbiology (iAMB), Aachen Biology and Biotechnology (ABBt), RWTH Aachen University, Worringerweg 1, Aachen, Germany.
PLoS Comput Biol ; 13(2): e1005280, 2017 02.
Article em En | MEDLINE | ID: mdl-28151932
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Farmacocinética / Transdução de Sinais / Doença Hepática Induzida por Substâncias e Drogas / Fígado / Modelos Biológicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Farmacocinética / Transdução de Sinais / Doença Hepática Induzida por Substâncias e Drogas / Fígado / Modelos Biológicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article