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The Transcription Factor MYB29 Is a Regulator of ALTERNATIVE OXIDASE1a.
Zhang, Xinhua; Ivanova, Aneta; Vandepoele, Klaas; Radomiljac, Jordan; Van de Velde, Jan; Berkowitz, Oliver; Willems, Patrick; Xu, Yue; Ng, Sophia; Van Aken, Olivier; Duncan, Owen; Zhang, Botao; Storme, Veronique; Chan, Kai Xun; Vaneechoutte, Dries; Pogson, Barry James; Van Breusegem, Frank; Whelan, James; De Clercq, Inge.
Afiliação
  • Zhang X; Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China (X.Z).
  • Ivanova A; Department of Animal, Plant, and Soil Science, Australian Research Council Centre of Excellence in Plant Energy Biology, La Trobe University, Bundoora, Victoria 3086, Australia (X.Z., A.I., J.R., O.B., Y.X., B.Z., J.W., I.D.C.).
  • Vandepoele K; Department of Animal, Plant, and Soil Science, Australian Research Council Centre of Excellence in Plant Energy Biology, La Trobe University, Bundoora, Victoria 3086, Australia (X.Z., A.I., J.R., O.B., Y.X., B.Z., J.W., I.D.C.).
  • Radomiljac J; Center for Plant Systems Biology, VIB, 9052 Ghent, Belgium (K.V., J.V.d.V., P.W., V.S., D.V., F.V.B., I.D.C.).
  • Van de Velde J; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (K.V., J.V.d.V., P.W., V.S., D.V., F.V.B., I.D.C.).
  • Berkowitz O; Department of Animal, Plant, and Soil Science, Australian Research Council Centre of Excellence in Plant Energy Biology, La Trobe University, Bundoora, Victoria 3086, Australia (X.Z., A.I., J.R., O.B., Y.X., B.Z., J.W., I.D.C.).
  • Willems P; Center for Plant Systems Biology, VIB, 9052 Ghent, Belgium (K.V., J.V.d.V., P.W., V.S., D.V., F.V.B., I.D.C.).
  • Xu Y; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (K.V., J.V.d.V., P.W., V.S., D.V., F.V.B., I.D.C.).
  • Ng S; Department of Animal, Plant, and Soil Science, Australian Research Council Centre of Excellence in Plant Energy Biology, La Trobe University, Bundoora, Victoria 3086, Australia (X.Z., A.I., J.R., O.B., Y.X., B.Z., J.W., I.D.C.).
  • Van Aken O; Center for Plant Systems Biology, VIB, 9052 Ghent, Belgium (K.V., J.V.d.V., P.W., V.S., D.V., F.V.B., I.D.C.).
  • Duncan O; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (K.V., J.V.d.V., P.W., V.S., D.V., F.V.B., I.D.C.).
  • Zhang B; Medical Biotechnology Center, VIB, 9000 Ghent, Belgium (P.W.).
  • Storme V; Department of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.).
  • Chan KX; Department of Animal, Plant, and Soil Science, Australian Research Council Centre of Excellence in Plant Energy Biology, La Trobe University, Bundoora, Victoria 3086, Australia (X.Z., A.I., J.R., O.B., Y.X., B.Z., J.W., I.D.C.).
  • Vaneechoutte D; Australian Research Council Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley, Western Australia 6009, Australia (S.N., O.V.A., O.D.); and.
  • Pogson BJ; Australian Research Council Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley, Western Australia 6009, Australia (S.N., O.V.A., O.D.); and.
  • Van Breusegem F; Australian Research Council Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley, Western Australia 6009, Australia (S.N., O.V.A., O.D.); and.
  • Whelan J; Department of Animal, Plant, and Soil Science, Australian Research Council Centre of Excellence in Plant Energy Biology, La Trobe University, Bundoora, Victoria 3086, Australia (X.Z., A.I., J.R., O.B., Y.X., B.Z., J.W., I.D.C.).
  • De Clercq I; Center for Plant Systems Biology, VIB, 9052 Ghent, Belgium (K.V., J.V.d.V., P.W., V.S., D.V., F.V.B., I.D.C.).
Plant Physiol ; 173(3): 1824-1843, 2017 03.
Article em En | MEDLINE | ID: mdl-28167700
ABSTRACT
Plants sense and integrate a variety of signals from the environment through different interacting signal transduction pathways that involve hormones and signaling molecules. Using ALTERNATIVE OXIDASE1a (AOX1a) gene expression as a model system of retrograde or stress signaling between mitochondria and the nucleus, MYB DOMAIN PROTEIN29 (MYB29) was identified as a negative regulator (regulator of alternative oxidase1a 7 [rao7] mutant) in a genetic screen of Arabidopsis (Arabidopsis thaliana). rao7/myb29 mutants have increased levels of AOX1a transcript and protein compared to wild type after induction with antimycin A. A variety of genes previously associated with the mitochondrial stress response also display enhanced transcript abundance, indicating that RAO7/MYB29 negatively regulates mitochondrial stress responses in general. Meta-analysis of hormone-responsive marker genes and identification of downstream transcription factor networks revealed that MYB29 functions in the complex interplay of ethylene, jasmonic acid, salicylic acid, and reactive oxygen species signaling by regulating the expression of various ETHYLENE RESPONSE FACTOR and WRKY transcription factors. Despite an enhanced induction of mitochondrial stress response genes, rao7/myb29 mutants displayed an increased sensitivity to combined moderate light and drought stress. These results uncover interactions between mitochondrial retrograde signaling and the regulation of glucosinolate biosynthesis, both regulated by RAO7/MYB29. This common regulator can explain why perturbation of the mitochondrial function leads to transcriptomic responses overlapping with responses to biotic stress.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxirredutases / Proteínas de Plantas / Fatores de Transcrição / Arabidopsis / Regulação da Expressão Gênica de Plantas / Proteínas Mitocondriais / Proteínas de Arabidopsis Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxirredutases / Proteínas de Plantas / Fatores de Transcrição / Arabidopsis / Regulação da Expressão Gênica de Plantas / Proteínas Mitocondriais / Proteínas de Arabidopsis Idioma: En Ano de publicação: 2017 Tipo de documento: Article