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Anti-GD2-ch14.18/CHO coated nanoparticles mediate glioblastoma (GBM)-specific delivery of the aromatase inhibitor, Letrozole, reducing proliferation, migration and chemoresistance in patient-derived GBM tumor cells.
Tivnan, Amanda; Heilinger, Tatjana; Ramsey, Joanne M; O'Connor, Gemma; Pokorny, Jenny L; Sarkaria, Jann N; Stringer, Brett W; Day, Bryan W; Boyd, Andrew W; Kim, Ella L; Lode, Holger N; Cryan, Sally-Ann; Prehn, Jochen H M.
Afiliação
  • Tivnan A; Centre for Systems Medicine, Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, York House, Dublin 2, Ireland.
  • Heilinger T; Centre for Systems Medicine, Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, York House, Dublin 2, Ireland.
  • Ramsey JM; IMC Fachhochschule Krems, University of Applied Sciences, Krems, Austria.
  • O'Connor G; School of Pharmacy, Royal College of Surgeons in Ireland, York House, Dublin 2, Ireland & Tissue Engineering Research Group, Department of Anatomy, RCSI and Centre for Research in Medical Devices (CURAM), NUIG, Ireland.
  • Pokorny JL; School of Pharmacy, Royal College of Surgeons in Ireland, York House, Dublin 2, Ireland & Tissue Engineering Research Group, Department of Anatomy, RCSI and Centre for Research in Medical Devices (CURAM), NUIG, Ireland.
  • Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, MN, United States of America.
  • Stringer BW; Department of Neurosurgery, Stanford University, Stanford, CA 94305, USA.
  • Day BW; Department of Radiation Oncology, Mayo Clinic, Rochester, MN, United States of America.
  • Boyd AW; Brain Cancer Research Unit, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Kim EL; Brain Cancer Research Unit, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Lode HN; Brain Cancer Research Unit, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Cryan SA; Laboratory of Neurooncology, Department of Neurosurgery, Johannes Gutenberg University Medical Center, Mainz, Germany.
  • Prehn JH; Department of Paediatrics and Paediatric Haematology/Oncology, University of Greifswald, Greifswald, Germany.
Oncotarget ; 8(10): 16605-16620, 2017 Mar 07.
Article em En | MEDLINE | ID: mdl-28178667

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triazóis / Neoplasias Encefálicas / Imunotoxinas / Glioblastoma / Inibidores da Aromatase / Nanopartículas / Antineoplásicos / Nitrilas Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triazóis / Neoplasias Encefálicas / Imunotoxinas / Glioblastoma / Inibidores da Aromatase / Nanopartículas / Antineoplásicos / Nitrilas Idioma: En Ano de publicação: 2017 Tipo de documento: Article