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A high-throughput small molecule screen identifies synergism between DNA methylation and Aurora kinase pathways for X reactivation.
Lessing, Derek; Dial, Thomas O; Wei, Chunyao; Payer, Bernhard; Carrette, Lieselot L G; Kesner, Barry; Szanto, Attila; Jadhav, Ajit; Maloney, David J; Simeonov, Anton; Theriault, Jimmy; Hasaka, Thomas; Bedalov, Antonio; Bartolomei, Marisa S; Lee, Jeannie T.
Afiliação
  • Lessing D; Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, MA 02114.
  • Dial TO; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114.
  • Wei C; Department of Genetics, Harvard Medical School, Boston, MA 02115.
  • Payer B; Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, MA 02114.
  • Carrette LL; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114.
  • Kesner B; Department of Genetics, Harvard Medical School, Boston, MA 02115.
  • Szanto A; Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, MA 02114.
  • Jadhav A; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114.
  • Maloney DJ; Department of Genetics, Harvard Medical School, Boston, MA 02115.
  • Simeonov A; Centre for Genomic Regulation, 08003 Barcelona, Spain.
  • Theriault J; Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, MA 02114.
  • Hasaka T; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114.
  • Bedalov A; Department of Genetics, Harvard Medical School, Boston, MA 02115.
  • Bartolomei MS; Center for Medical Genetics, Ghent University, 9000 Ghent, Belgium.
  • Lee JT; Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, MA 02114.
Proc Natl Acad Sci U S A ; 113(50): 14366-14371, 2016 12 13.
Article em En | MEDLINE | ID: mdl-28182563
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Metilação de DNA / Inativação do Cromossomo X / Aurora Quinases Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Metilação de DNA / Inativação do Cromossomo X / Aurora Quinases Idioma: En Ano de publicação: 2016 Tipo de documento: Article