Glomerular C4d deposits can mark structural capillary wall remodelling in thrombotic microangiopathy and transplant glomerulopathy: C4d beyond active antibody-mediated injury: a retrospective study.

Gasim, Adil H; Chua, Jamie S; Wolterbeek, Ron; Schmitz, John; Weimer, Eric; Singh, Harsharan K; Nickeleit, Volker

Gasim, Adil H; Chua, Jamie S; Wolterbeek, Ron; Schmitz, John; Weimer, Eric; Singh, Harsharan K; Nickeleit, Volker.

Afiliação

Gasim AH; Division of Nephropathology, Department of Pathology and Laboratory Medicine, The University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Chua JS; Division of Nephropathology, Department of Pathology and Laboratory Medicine, The University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Wolterbeek R; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Schmitz J; Department of Medical Statistics and Bio-Informatics, Leiden University Medical Center, Leiden, The Netherlands.
Weimer E; Department of Pathology and Laboratory Medicine, McLendon Clinical Laboratories, The University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Singh HK; Department of Pathology and Laboratory Medicine, McLendon Clinical Laboratories, The University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Nickeleit V; Division of Nephropathology, Department of Pathology and Laboratory Medicine, The University of North Carolina School of Medicine, Chapel Hill, NC, USA.

Transpl Int ; 30(5): 519-532, 2017 May.

Article em En | MEDLINE | ID: mdl-28207978

Assuntos

Complemento C4b/metabolismo; Rejeição de Enxerto/imunologia; Glomérulos Renais/imunologia; Fragmentos de Peptídeos/metabolismo; Microangiopatias Trombóticas/imunologia; Remodelação Vascular; Feminino; Rejeição de Enxerto/patologia; Humanos; Glomérulos Renais/ultraestrutura; Masculino; Estudos Retrospectivos; Microangiopatias Trombóticas/patologia; Microangiopatias Trombóticas/fisiopatologia

Palavras-chave

complement factor C4d; electron microscopy; glomerular basement membrane duplication; immunofluorescence microscopy; thrombotic microangiopathy; transplant glomerulopathy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Complemento C4b / Microangiopatias Trombóticas / Remodelação Vascular / Rejeição de Enxerto / Glomérulos Renais Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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