[Role of dipeptidyl peptidase-4 and its inhibitor in the respiratory diseases].
Zhong Nan Da Xue Xue Bao Yi Xue Ban
; 42(1): 108-112, 2017 Jan 28.
Article
em Zh
| MEDLINE
| ID: mdl-28216506
ABSTRACT
Dipeptidyl peptidase-4 (DPP-4) is known as a highly conserved type II transmembraneous glycoprotein widely distributed in a variety of tissues and cells, and expressed in the peripheral blood as a soluble form. It has been reported that DPP4 play a distinct role in the physiological and pathological processes, such as immune regulation, inflammatory reaction, cell adhesion, and cell apoptosis. DPP4 inhibitor showes an incredible effect on the control of blood glucose and it is thought as a newly-developed drug for diabetes, especially in regulation of post-prandial glycemia. It has been reported that DPP4 plays a potential role in many respiratory diseases, especially in the pathogenesis of asthma.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Respiratórias
/
Dipeptidil Peptidase 4
/
Inibidores da Dipeptidil Peptidase IV
Idioma:
Zh
Ano de publicação:
2017
Tipo de documento:
Article