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Combination of l-Carnitine with Lipophilic Linkage-Donating Gemcitabine Derivatives as Intestinal Novel Organic Cation Transporter 2-Targeting Oral Prodrugs.
Wang, Gang; Chen, Hongxiang; Zhao, Dongyang; Ding, Dawei; Sun, Mengchi; Kou, Longfa; Luo, Cong; Zhang, Dong; Yi, Xiulin; Dong, Jinhua; Wang, Jian; Liu, Xiaohong; He, Zhonggui; Sun, Jin.
Afiliação
  • Wang G; School of Pharmacy, Shenyang Pharmaceutical University , Wenhua Road, Shenyang 110016, China.
  • Chen H; School of Pharmacy, Shenyang Pharmaceutical University , Wenhua Road, Shenyang 110016, China.
  • Zhao D; School of Pharmacy, Shenyang Pharmaceutical University , Wenhua Road, Shenyang 110016, China.
  • Ding D; School of Pharmacy, Shenyang Pharmaceutical University , Wenhua Road, Shenyang 110016, China.
  • Sun M; School of Pharmacy, Shenyang Pharmaceutical University , Wenhua Road, Shenyang 110016, China.
  • Kou L; School of Pharmacy, Shenyang Pharmaceutical University , Wenhua Road, Shenyang 110016, China.
  • Luo C; School of Pharmacy, Shenyang Pharmaceutical University , Wenhua Road, Shenyang 110016, China.
  • Zhang D; School of Pharmacy, Shenyang Pharmaceutical University , Wenhua Road, Shenyang 110016, China.
  • Yi X; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research , Tianjin, China.
  • Dong J; School of Pharmacy, Shenyang Pharmaceutical University , Wenhua Road, Shenyang 110016, China.
  • Wang J; Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Ministry of Education , Shenyang, China.
  • Liu X; School of Pharmacy, Shenyang Pharmaceutical University , Wenhua Road, Shenyang 110016, China.
  • He Z; School of Pharmacy, Shenyang Pharmaceutical University , Wenhua Road, Shenyang 110016, China.
  • Sun J; School of Pharmacy, Shenyang Pharmaceutical University , Wenhua Road, Shenyang 110016, China.
J Med Chem ; 60(6): 2552-2561, 2017 03 23.
Article em En | MEDLINE | ID: mdl-28234466
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Proteínas de Transporte de Cátions Orgânicos / Desoxicitidina / Antimetabólitos Antineoplásicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Proteínas de Transporte de Cátions Orgânicos / Desoxicitidina / Antimetabólitos Antineoplásicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article