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MicroRNAs in Lung Development and Disease.
Ameis, Dustin; Khoshgoo, Naghmeh; Iwasiow, Barbara M; Snarr, Phillip; Keijzer, Richard.
Afiliação
  • Ameis D; Departments of Surgery, Pediatrics and Child Health and Physiology and Pathophysiology, University of Manitoba, and The Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.
  • Khoshgoo N; Departments of Surgery, Pediatrics and Child Health and Physiology and Pathophysiology, University of Manitoba, and The Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.
  • Iwasiow BM; Departments of Surgery, Pediatrics and Child Health and Physiology and Pathophysiology, University of Manitoba, and The Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.
  • Snarr P; Departments of Surgery, Pediatrics and Child Health and Physiology and Pathophysiology, University of Manitoba, and The Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.
  • Keijzer R; Departments of Surgery, Pediatrics and Child Health and Physiology and Pathophysiology, University of Manitoba, and The Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada. Electronic address: richardkeijzer@gmail.com.
Paediatr Respir Rev ; 22: 38-43, 2017 Mar.
Article em En | MEDLINE | ID: mdl-28237418
MicroRNAs (miRNAs) are small (∼22 nucleotides), non-coding RNA molecules that regulate gene expression post-transcriptionally by inhibiting target mRNAs. Research into the roles of miRNAs in lung development and disease is at the early stages. In this review, we discuss the role of miRNAs in pediatric respiratory disease, including cystic fibrosis, asthma, and bronchopulmonary dysplasia.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: MicroRNAs / Pulmão / Pneumopatias Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: MicroRNAs / Pulmão / Pneumopatias Idioma: En Ano de publicação: 2017 Tipo de documento: Article