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Systemic autoimmunity induced by the TLR7/8 agonist Resiquimod causes myocarditis and dilated cardiomyopathy in a new mouse model of autoimmune heart disease.
Hasham, Muneer G; Baxan, Nicoleta; Stuckey, Daniel J; Branca, Jane; Perkins, Bryant; Dent, Oliver; Duffy, Ted; Hameed, Tolani S; Stella, Sarah E; Bellahcene, Mohammed; Schneider, Michael D; Harding, Sian E; Rosenthal, Nadia; Sattler, Susanne.
Afiliação
  • Hasham MG; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
  • Baxan N; Biological Imaging Centre, Department of Medicine, Imperial College London, London W12 0NN, UK.
  • Stuckey DJ; Centre for Advanced Biomedical Imaging, Division of Medicine, University College London, London WC1E 6DD, UK.
  • Branca J; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
  • Perkins B; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
  • Dent O; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Duffy T; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
  • Hameed TS; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Stella SE; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Bellahcene M; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Schneider MD; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Harding SE; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Rosenthal N; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
  • Sattler S; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
Dis Model Mech ; 10(3): 259-270, 2017 03 01.
Article em En | MEDLINE | ID: mdl-28250051

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cardiomiopatia Dilatada / Autoimunidade / Receptor 7 Toll-Like / Receptor 8 Toll-Like / Imidazóis / Miocardite Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cardiomiopatia Dilatada / Autoimunidade / Receptor 7 Toll-Like / Receptor 8 Toll-Like / Imidazóis / Miocardite Idioma: En Ano de publicação: 2017 Tipo de documento: Article