Differential decrease in soluble and DNA-bound telomerase in senescent human fibroblasts.

Yehuda, Snir; Yanai, Hagai; Priel, Esther; Fraifeld, Vadim E

Yehuda, Snir; Yanai, Hagai; Priel, Esther; Fraifeld, Vadim E.

Afiliação

Yehuda S; The Shraga Segal Department of Microbiology, Immunology and Genetics, Center for Multidisciplinary Research on Aging, Ben-Gurion University of the Negev, POB 653, 8410501, Beer Sheva, Israel.
Yanai H; The Shraga Segal Department of Microbiology, Immunology and Genetics, Center for Multidisciplinary Research on Aging, Ben-Gurion University of the Negev, POB 653, 8410501, Beer Sheva, Israel.
Priel E; The Shraga Segal Department of Microbiology, Immunology and Genetics, Center for Multidisciplinary Research on Aging, Ben-Gurion University of the Negev, POB 653, 8410501, Beer Sheva, Israel.
Fraifeld VE; The Shraga Segal Department of Microbiology, Immunology and Genetics, Center for Multidisciplinary Research on Aging, Ben-Gurion University of the Negev, POB 653, 8410501, Beer Sheva, Israel. vadim.fraifeld@gmail.com.

Biogerontology ; 18(4): 525-533, 2017 08.

Article em En | MEDLINE | ID: mdl-28251405

Assuntos

Senescência Celular; DNA/metabolismo; Fibroblastos/enzimologia; Telomerase/metabolismo; Encurtamento do Telômero; Telômero/enzimologia; Proliferação de Células; Células Cultivadas; Regulação para Baixo; Humanos; Solubilidade; Fatores de Tempo

Palavras-chave

Cellular senescence; Dermal fibroblasts; Primary cultures; Telomerase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Telômero / Senescência Celular / Telomerase / Encurtamento do Telômero / Fibroblastos Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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