Aberrant Immunological Synapses Driven by Leukemic Antigen-Presenting Cells.
Methods Mol Biol
; 1584: 533-544, 2017.
Article
em En
| MEDLINE
| ID: mdl-28255724
Aberrant immune synapse formation between antigen-presenting and immune effector cells is a central mediator of immune dysfunction and can be observed across several haematologic malignancies. Here, we describe the cell preparation, conjugation and immune synapse quantification of B and T cells obtained from patients with leukaemia and the adaptions required when using cells from murine models of disease.
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Base de dados:
MEDLINE
Assunto principal:
Linfócitos B
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Linfócitos T
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Leucemia
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Sinapses Imunológicas
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Células Apresentadoras de Antígenos
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article