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Follicular lymphoma transforming into diffuse large B-cell lymphoma in spleen: Simultaneous appearance of both on 18F-FDG PET/CT and histology.
Makis, William; Ciarallo, Anthony; Petrogiannis-Haliotis, Tina; Rosenberg, Arthur; Probst, Stephan.
Afiliação
  • Makis W; Department of Diagnostic Imaging, Cross Cancer Institute, 11560 University Ave NW, Edmonton, Alberta, T6G 1Z2, Canada. Electronic address: makisw79@yahoo.com.
  • Ciarallo A; Department of Nuclear Medicine, MUHC McGill University Health Centre, Glen Site, 1001 Boul Decarie, Montreal, Quebec, H4A 3J1, Canada.
  • Petrogiannis-Haliotis T; Department of Pathology, Jewish General Hospital, Montreal, QC, Canada.
  • Rosenberg A; Department of Pathology, Jewish General Hospital, Montreal, QC, Canada.
  • Probst S; Department of Nuclear Medicine, Jewish General Hospital, Montreal, QC, Canada.
Clin Imaging ; 43: 88-92, 2017.
Article em En | MEDLINE | ID: mdl-28259031
ABSTRACT
Low grade lymphoma may transform into a more aggressive lymphoma and this transformation is usually associated with a poor outcome. A 65year old man presented with two metabolically active splenic lesions on a staging [18F] fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT). Histologic evaluation post splenectomy confirmed the presence of two clonally related lymphomas a follicular lymphoma (FL) and a diffuse large B-cell lymphoma (DLBCL). Molecular genetic studies confirmed that the DLBCL lesions arose from a pre-existing FL. We present the 18F-FDG PET/CT imaging characteristics of both lymphoma types which were simultaneously present in the spleen.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Baço / Transformação Celular Neoplásica / Linfoma Folicular / Linfoma Difuso de Grandes Células B / Fluordesoxiglucose F18 / Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Baço / Transformação Celular Neoplásica / Linfoma Folicular / Linfoma Difuso de Grandes Células B / Fluordesoxiglucose F18 / Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada Idioma: En Ano de publicação: 2017 Tipo de documento: Article