Viability and Biomechanics of Bare Diced Cartilage Grafts in Experimental Study.
J Craniofac Surg
; 28(6): 1445-1450, 2017 Sep.
Article
em En
| MEDLINE
| ID: mdl-28277476
ABSTRACT
OBJECTIVE:
To assess the viability and biomechanics of bare diced cartilage grafts.METHODS:
Cartilage samples were collected from 1 ear in 15 rabbits as well as costal cartilage. Each rabbit was inserted bare diced- and single-strip costal-cartilage grafts, respectively, into paraspinal subcutaneous pockets after euthanasia at 2 months, specimens were weighed, with diced cartilage grafts examined histomorphologically by hematoxylin-eosin staining, masson trichrome staining, and immunohistochemistry. Finally, biomechanical properties of grafts were assessed.RESULTS:
Bare diced cartilage grafts were connected into an integrated mass after 2 months, and inward growth of fibrous tissues and angiogenesis were observed. Mean wet weights of diced cartilage grafts were 1.603â±â0.278 and 1.662â±â0.204âg pre- and postoperation, respectively; those of costal cartilage grafts were 0.053â±â0.008 and 0.058â±â0.008âg, respectively. In compression assays, mean modulus values of elasticity at yield in diced- and costal-cartilage grafts were 7.65â±â0.59 and 22.30â±â1.15 MPa, respectively (Pâ<â0.05); mean stress values were 4.07â±â0.38 and 12.50â±â1.15 MPa, respectively (Pâ<â0.05). In the tensile test, mean modulus values of elasticity at yield of diced- and costal-cartilage grafts were 4.70â±â0.78 and 10.59â±â1.39 MPa, respectively (Pâ<â0.05), mean stress values were 0.82â±â0.05 and 1.76â±â0.21 MPa, respectively (Pâ<â0.05).CONCLUSIONS:
Diced cartilage grafts had favorable viability and growth. Despite reduced elasticity and stress values, they still can be served as substitute for supportive filling materials.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Sobrevivência de Tecidos
/
Elasticidade
/
Cartilagem Costal
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article