Human Second Window Pre-Conditioning and Post-Conditioning by Nitrite Is Influenced by a Common Polymorphism in Mitochondrial Aldehyde Dehydrogenase.

Ormerod, Julian O M; Evans, Jonathan D W; Contractor, Hussain; Beretta, Matteo; Arif, Sayqa; Fernandez, Bernadette O; Feelisch, Martin; Mayer, Bernd; Kharbanda, Rajesh K; Frenneaux, Michael P; Ashrafian, Houman.

Afiliação

Ormerod JO; Oxford Heart Centre, Oxford University Hospitals, Oxford, United Kingdom.
Evans JD; Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Contractor H; Department of Cardiovascular Medicine, West Wing, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.
Beretta M; Department of Pharmacology and Toxicology, Karl-Franzens-Universität, Graz, Austria.
Arif S; Department of Cardiovascular Medicine, Medical School, University of Birmingham, Birmingham, United Kingdom.
Fernandez BO; Faculty of Medicine, Clinical and Experimental Sciences, University of Southampton, Southampton, United Kingdom.
Feelisch M; Faculty of Medicine, Clinical and Experimental Sciences, University of Southampton, Southampton, United Kingdom.
Mayer B; Department of Pharmacology and Toxicology, Karl-Franzens-Universität, Graz, Austria.
Kharbanda RK; Oxford Heart Centre, Oxford University Hospitals, Oxford, United Kingdom.
Frenneaux MP; Medical School, University of East Anglia, Norwich, United Kingdom.
Ashrafian H; Department of Cardiovascular Medicine, West Wing, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.

JACC Basic Transl Sci ; 2(1): 13-21, 2017 Feb.

Article em En | MEDLINE | ID: mdl-28280793

Palavras-chave

ALDH2, mitochondrial aldehyde dehydrogenase; Ach, acetylcholine; FBF, forearm blood flow; FBF-R, forearm blood flow ratio; GTN, glyceryl trinitrate; IR, ischemiareperfusion; RIPC, remote ischemic pre-conditioning; cytoprotection; endothelium; nitric oxide; nitrite; reperfusion injury

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article