Erythropoietin (EPO) ameliorates obesity and glucose homeostasis by promoting thermogenesis and endocrine function of classical brown adipose tissue (BAT) in diet-induced obese mice.

Kodo, Kazuki; Sugimoto, Satoru; Nakajima, Hisakazu; Mori, Jun; Itoh, Ikuyo; Fukuhara, Shota; Shigehara, Keiichi; Nishikawa, Taichiro; Kosaka, Kitaro; Hosoi, Hajime

Kodo, Kazuki; Sugimoto, Satoru; Nakajima, Hisakazu; Mori, Jun; Itoh, Ikuyo; Fukuhara, Shota; Shigehara, Keiichi; Nishikawa, Taichiro; Kosaka, Kitaro; Hosoi, Hajime.

Afiliação

Kodo K; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto City, Japan.
Sugimoto S; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto City, Japan.
Nakajima H; Department of Pediatrics, Ayabe Municipal Hospital, Ayabe City, Japan.
Mori J; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto City, Japan.
Itoh I; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto City, Japan.
Fukuhara S; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto City, Japan.
Shigehara K; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto City, Japan.
Nishikawa T; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto City, Japan.
Kosaka K; Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto City, Japan.
Hosoi H; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto City, Japan.

PLoS One ; 12(3): e0173661, 2017.

Article em En | MEDLINE | ID: mdl-28288167

Assuntos

Tecido Adiposo Marrom/metabolismo; Eritropoetina/metabolismo; Eritropoetina/farmacologia; Obesidade/etiologia; Termogênese/fisiologia; Adipócitos/efeitos dos fármacos; Adipócitos/metabolismo; Tecido Adiposo Marrom/efeitos dos fármacos; Tecido Adiposo Branco/efeitos dos fármacos; Tecido Adiposo Branco/metabolismo; Animais; Fármacos Antiobesidade/farmacologia; Proteínas de Ligação a DNA/metabolismo; Dieta Hiperlipídica/efeitos adversos; Metabolismo Energético/efeitos dos fármacos; Fatores de Crescimento de Fibroblastos/metabolismo; Intolerância à Glucose/tratamento farmacológico; Teste de Tolerância a Glucose; Resistência à Insulina; Masculino; Camundongos Endogâmicos C57BL; Obesidade/tratamento farmacológico; Termogênese/efeitos dos fármacos; Fatores de Transcrição/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tecido Adiposo Marrom / Eritropoetina / Termogênese / Obesidade Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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