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3-O-(Z)-coumaroyloleanolic acid overcomes Cks1b-induced chemoresistance in lung cancer by inhibiting Hsp90 and MEK pathways.
Wang, He; Sun, Mingna; Guo, Jiayi; Ma, Lei; Jiang, Hui; Gu, Liang; Wen, Huaying; Liao, Siyan; Chen, Jingqi; Zeng, Bohang; Li, Yongmei; Li, Yueshan; Yu, Xiyong; Feng, Yinghong; Zhou, Yi.
Afiliação
  • Wang H; The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510260, China; The College of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong 510436, China.
  • Sun M; The College of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong 510436, China.
  • Guo J; The College of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong 510436, China.
  • Ma L; The College of Pharmaceutics Science, Guangdong Pharmaceutics Science University, Guangzhou, Guangdong 510412, China.
  • Jiang H; The College of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong 510436, China.
  • Gu L; The College of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong 510436, China.
  • Wen H; The College of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong 510436, China.
  • Liao S; The College of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong 510436, China.
  • Chen J; The College of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong 510436, China.
  • Zeng B; The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510260, China.
  • Li Y; The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510356, China.
  • Li Y; The College of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong 510436, China.
  • Yu X; The College of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong 510436, China.
  • Feng Y; The College of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong 510436, China; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MA 20814, USA. Electronic address: yh_feng111@163.com.
  • Zhou Y; The College of Pharmaceutics Science, Guangzhou Medical University, Guangzhou, Guangdong 510436, China. Electronic address: zhouyi0264@gzhmu.edu.cn.
Biochem Pharmacol ; 135: 35-49, 2017 07 01.
Article em En | MEDLINE | ID: mdl-28288818
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Oleanólico / Proteínas de Choque Térmico HSP90 / Resistencia a Medicamentos Antineoplásicos / MAP Quinase Quinase Quinases / Quinases relacionadas a CDC2 e CDC28 / Neoplasias Pulmonares Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Oleanólico / Proteínas de Choque Térmico HSP90 / Resistencia a Medicamentos Antineoplásicos / MAP Quinase Quinase Quinases / Quinases relacionadas a CDC2 e CDC28 / Neoplasias Pulmonares Idioma: En Ano de publicação: 2017 Tipo de documento: Article