[Azilsartan Medoxomil Capabilities in Arterial Hypertension and Obesity].
Kardiologiia
; 56(11): 108-112, 2016 12.
Article
em Ru
| MEDLINE
| ID: mdl-28290827
ABSTRACT
Arterial hypertension (AH) is one of the most common cardiovascular disease. Angiotensin II (AT II), the hormone of renin-angiotensin-aldosterone system, realizes its negative effects through AT 1 receptors - application point of angiotensin receptor blockers (ARB). Due to different dissociation AT 1 receptors properties some ARBs are more effective than others. Multiply multicenter randomized and observational studies approve the effectiveness and safety of azilsartan medoxomil in patients with AH 1-2 grade. Several preclinical studies have shown the additional properties of azilsartan, including increase of insulin sensitivity, cardio- and nephron protection in obesity. In our clinical case we showed the positive influence of azilsartan medoxomil on clinic and ambulatory blood pressure, 24-hour aortic stiffness parameters, longitudinal left ventricular strain in patient with AH and obesity.
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Base de dados:
MEDLINE
Assunto principal:
Oxidiazóis
/
Benzimidazóis
/
Bloqueadores do Receptor Tipo 1 de Angiotensina II
/
Hipertensão
/
Anti-Hipertensivos
Idioma:
Ru
Ano de publicação:
2016
Tipo de documento:
Article