[Possible Choice of New Oral Anticoagulants With Non-Valvular Atrial Fibrillation: a Review of Meta-Analyzes].

ABSTRACT

This review presents the results of a meta-analysis including data from all four studies of new oral anticoagulants for the prevention of stroke or systemic embolism in patients with non-valvular atrial fibrillation. It was found that all of the drugs had a favorable risk profile/efficiency, and provides a significant reduction in the incidence of stroke, intracranial hemorrhage and mortality. This increases the number of gastrointestinal bleeding. The relative efficacy and safety of new oral anticoagulants is consistent in patients with different clinical characteristics. These data provide a more complete picture of the new oral anticoagulants as a therapeutic method of reducing the risk of stroke in this patient population.