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Diagnostic capability of colon capsule endoscopy for advanced colorectal cancer: A pilot study.
Ota, Yumiko; Yamada, Atsuo; Kobayashi, Yuka; Niikura, Ryota; Shimpoh, Takayuki; Narita, Akiko; Yoshida, Shuntaro; Suzuki, Nobumi; Watabe, Hirotsugu; Hirata, Yoshihiro; Ishihara, Soichiro; Sunami, Eiji; Watanabe, Toshiaki; Koike, Kazuhiko.
Afiliação
  • Ota Y; Department of Gastroenterology, The University of Tokyo, Tokyo, Japan.
  • Yamada A; Department of Gastroenterology, The University of Tokyo, Tokyo, Japan.
  • Kobayashi Y; Department of Gastroenterology, The University of Tokyo, Tokyo, Japan.
  • Niikura R; Department of Gastroenterology, The University of Tokyo, Tokyo, Japan.
  • Shimpoh T; Department of Gastroenterology, The University of Tokyo, Tokyo, Japan.
  • Narita A; Department of Gastroenterology, The University of Tokyo, Tokyo, Japan.
  • Yoshida S; Department of Gastroenterology, The University of Tokyo, Tokyo, Japan.
  • Suzuki N; Department of Endoscopy and Endoscopic Surgery, The University of Tokyo, Tokyo, Japan.
  • Watabe H; Department of Gastroenterology, The Institute for Adult Diseases Asahi Life Foundation, Tokyo, Japan.
  • Hirata Y; Wakamiya Watabe Clinic, Chiba, Japan.
  • Ishihara S; Department of Gastroenterology, The University of Tokyo, Tokyo, Japan.
  • Sunami E; Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Watanabe T; Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Koike K; Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Dig Endosc ; 29(6): 695-701, 2017 Sep.
Article em En | MEDLINE | ID: mdl-28295697
ABSTRACT
BACKGROUND AND

AIM:

Colon capsule endoscopy (CCE) is a safe and effective method for detecting lesions in the colon. However, the sensitivity of CCE in detecting advanced colorectal cancer (CRC) has not been sufficiently evaluated. Therefore, the aim of the present study was to assess the sensitivity of CCE in detecting advanced CRC.

METHODS:

Patients previously diagnosed with advanced CRC by conventional colonoscopy underwent CCE. Primary outcome measure was the sensitivity of CCE in detecting advanced CRC per patient and per lesion. Secondary parameters measured were the sensitivity of CCE in detecting polyps ≥6 mm and ≥10 mm in size in a per-lesion analysis and the safety of CCE.

RESULTS:

Of the 21 advanced CRC lesions in 20 patients, 17 were detected by CCE. The per-patient and per-lesion sensitivities of CCE for detecting advanced CRC lesions were 85% (95% confidence interval [CI] 62-97%) and 81% (95% CI 58-95%), respectively. All advanced CRC lesions were diagnosed in the accessible region by CCE while the capsule was still functional. A significant association was found between incomplete CCE and failure to diagnose advanced CRC. No severe adverse events occurred.

CONCLUSION:

The diagnostic capability of CCE in detecting advanced CRC was limited in cases of procedure incompletion. Refining procedures to increase CCE procedure completion rates are required to enhance CRC detection.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Colonoscopia / Endoscopia por Cápsula Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Colonoscopia / Endoscopia por Cápsula Idioma: En Ano de publicação: 2017 Tipo de documento: Article