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Genome-wide mapping of histone H3K9me2 in acute myeloid leukemia reveals large chromosomal domains associated with massive gene silencing and sites of genome instability.
Salzberg, Anna C; Harris-Becker, Abigail; Popova, Evgenya Y; Keasey, Nikki; Loughran, Thomas P; Claxton, David F; Grigoryev, Sergei A.
Afiliação
  • Salzberg AC; Division of Biostatistics and Bioinformatics and Penn State Institute for Personalized Medicine, Hershey, Pennsylvania, United States of America.
  • Harris-Becker A; Penn State College of Medicine, Dept. Biochemistry & Molecular Biology, H171, Hershey, Pennsylvania, United States of America.
  • Popova EY; Penn State College of Medicine, Department of Neural and Behavioral Sciences, Hershey, Pennsylvania, United States of America.
  • Keasey N; Penn State Cancer Institute; Milton S. Hershey Medical Center, 500 University Drive, Hershey, Pennsylvania, United States of America.
  • Loughran TP; University of Virginia Cancer Center, Charlottesville, Virginia, United States of America.
  • Claxton DF; Penn State Cancer Institute; Milton S. Hershey Medical Center, 500 University Drive, Hershey, Pennsylvania, United States of America.
  • Grigoryev SA; Penn State College of Medicine, Dept. Biochemistry & Molecular Biology, H171, Hershey, Pennsylvania, United States of America.
PLoS One ; 12(3): e0173723, 2017.
Article em En | MEDLINE | ID: mdl-28301528
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histonas / Leucemia Mieloide Aguda / Mapeamento Cromossômico / Inativação Gênica / Instabilidade Genômica Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histonas / Leucemia Mieloide Aguda / Mapeamento Cromossômico / Inativação Gênica / Instabilidade Genômica Idioma: En Ano de publicação: 2017 Tipo de documento: Article