Cure Rate of Fungal Keratitis With Antibacterial Therapy.
Cornea
; 36(5): 578-580, 2017 May.
Article
em En
| MEDLINE
| ID: mdl-28306602
ABSTRACT
PURPOSE:
To study the cure rate of fungal keratitis with moxifloxacin 0.3% monotherapy.METHODS:
A retrospective review of patients with culture-proven fungal keratitis who initially received moxifloxacin 0.3% monotherapy was performed.RESULTS:
Eleven patients with culture-proven fungal keratitis were initially treated with moxifloxacin. One case each of Curvularia and Alternaria keratitis resolved with moxifloxacin monotherapy (18%).CONCLUSIONS:
Moxifloxacin may have a significant clinical therapeutic effect in a subset of patients with fungal keratitis. Review of the literature in combination with the current study suggests that in patients with clinical features suggestive of fungal keratitis, if rapid diagnostic tests are negative or not available, pending culture results, initial therapy should include a fluoroquinolone (moxifloxacin or gatifloxacin) and/or an aminoglycoside (tobramycin or gentamicin).
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções Oculares Fúngicas
/
Fluoroquinolonas
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Ceratite
/
Antibacterianos
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article