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Structure-Enabled Discovery of a Stapled Peptide Inhibitor to Target the Oncogenic Transcriptional Repressor TLE1.
McGrath, Sally; Tortorici, Marcello; Drouin, Ludovic; Solanki, Savade; Vidler, Lewis; Westwood, Isaac; Gimeson, Peter; Van Montfort, Rob; Hoelder, Swen.
Afiliação
  • McGrath S; The Institute of Cancer Research, Division of Cancer Therapeutics Unit, Cancer Research UK Cancer Therapeutics Unit, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK.
  • Tortorici M; The Institute of Cancer Research, Division of Cancer Therapeutics Unit, Cancer Research UK Cancer Therapeutics Unit, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK.
  • Drouin L; The Institute of Cancer Research, Division of Cancer Therapeutics Unit, Cancer Research UK Cancer Therapeutics Unit, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK.
  • Solanki S; The Institute of Cancer Research, Division of Cancer Therapeutics Unit, Cancer Research UK Cancer Therapeutics Unit, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK.
  • Vidler L; The Institute of Cancer Research, Division of Cancer Therapeutics Unit, Cancer Research UK Cancer Therapeutics Unit, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK.
  • Westwood I; The Institute of Cancer Research, Division of Cancer Therapeutics Unit, Cancer Research UK Cancer Therapeutics Unit, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK.
  • Gimeson P; Malvern Instruments Nordic AB, Vallongatan 1, Uppsala, 752 28, Sweden.
  • Van Montfort R; Cancer Research (UK) Cancer Therapeutics Unit, Division of Cancer Therapeutics, Division of Structural Biology, The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK.
  • Hoelder S; The Institute of Cancer Research, Division of Cancer Therapeutics Unit, Cancer Research UK Cancer Therapeutics Unit, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK.
Chemistry ; 23(40): 9577-9584, 2017 Jul 18.
Article em En | MEDLINE | ID: mdl-28326635
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Peptídeos Cíclicos / Proteínas Repressoras Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Peptídeos Cíclicos / Proteínas Repressoras Idioma: En Ano de publicação: 2017 Tipo de documento: Article