Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Responses in Human Macrophages.

Olejnik, Judith; Forero, Adriana; Deflubé, Laure R; Hume, Adam J; Manhart, Whitney A; Nishida, Andrew; Marzi, Andrea; Katze, Michael G; Ebihara, Hideki; Rasmussen, Angela L; Mühlberger, Elke

Olejnik, Judith; Forero, Adriana; Deflubé, Laure R; Hume, Adam J; Manhart, Whitney A; Nishida, Andrew; Marzi, Andrea; Katze, Michael G; Ebihara, Hideki; Rasmussen, Angela L; Mühlberger, Elke.

Afiliação

Olejnik J; Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA.
Forero A; National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts, USA.
Deflubé LR; Department of Microbiology, University of Washington, Seattle, Washington, USA.
Hume AJ; Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA.
Manhart WA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts, USA.
Nishida A; Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA.
Marzi A; National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts, USA.
Katze MG; Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA.
Ebihara H; National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts, USA.
Rasmussen AL; Department of Microbiology, University of Washington, Seattle, Washington, USA.
Mühlberger E; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana, USA.

J Virol ; 91(11)2017 06 01.

Article em En | MEDLINE | ID: mdl-28331091

Assuntos

Ebolavirus/imunologia; Ebolavirus/patogenicidade; Interações Hospedeiro-Patógeno; Macrófagos/virologia; Receptor 4 Toll-Like/metabolismo; Animais; Linhagem Celular; Quimiocinas/imunologia; Quimiocinas/metabolismo; Chlorocebus aethiops; Citocinas/imunologia; Células Dendríticas/imunologia; Células Dendríticas/virologia; Ebolavirus/fisiologia; Perfilação da Expressão Gênica; Humanos; Fator Regulador 3 de Interferon/genética; Fator Regulador 3 de Interferon/imunologia; Interferons/imunologia; Macrófagos/imunologia; Macrófagos/metabolismo; Subunidade p50 de NF-kappa B/genética; Subunidade p50 de NF-kappa B/metabolismo; Receptor 4 Toll-Like/genética; Receptor 4 Toll-Like/imunologia; Células Vero; Virulência

Palavras-chave

Ebola virus; Reston virus; Toll-like receptor 4; Toll-like receptors; chemokines; cytokines; filovirus; host response; interferons; macrophages

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ebolavirus / Receptor 4 Toll-Like / Interações Hospedeiro-Patógeno / Macrófagos Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google