Chronic PARP-1 inhibition reduces carotid vessel remodeling and oxidative damage of the dorsal hippocampus in spontaneously hypertensive rats.

Eros, Krisztian; Magyar, Klara; Deres, Laszlo; Skazel, Arpad; Riba, Adam; Vamos, Zoltan; Kalai, Tamas; Gallyas, Ferenc; Sumegi, Balazs; Toth, Kalman; Halmosi, Robert

Eros, Krisztian; Magyar, Klara; Deres, Laszlo; Skazel, Arpad; Riba, Adam; Vamos, Zoltan; Kalai, Tamas; Gallyas, Ferenc; Sumegi, Balazs; Toth, Kalman; Halmosi, Robert.

Afiliação

Eros K; 1st Department of Medicine, Clinical Centre, University of Pecs, Pecs, Baranya, Hungary.
Magyar K; Szentagothai Research Centre, University of Pecs, Pecs, Baranya, Hungary.
Deres L; Department of Biochemistry and Medical Chemistry, Medical School, University of Pecs, Pecs, Baranya, Hungary.
Skazel A; 1st Department of Medicine, Clinical Centre, University of Pecs, Pecs, Baranya, Hungary.
Riba A; 1st Department of Medicine, Clinical Centre, University of Pecs, Pecs, Baranya, Hungary.
Vamos Z; Szentagothai Research Centre, University of Pecs, Pecs, Baranya, Hungary.
Kalai T; 1st Department of Medicine, Clinical Centre, University of Pecs, Pecs, Baranya, Hungary.
Gallyas F; 1st Department of Medicine, Clinical Centre, University of Pecs, Pecs, Baranya, Hungary.
Sumegi B; Szentagothai Research Centre, University of Pecs, Pecs, Baranya, Hungary.
Toth K; Szentagothai Research Centre, University of Pecs, Pecs, Baranya, Hungary.
Halmosi R; Department of Pathophysiology and Gerontology, Medical School, University of Pecs, Pecs, Baranya, Hungary.

PLoS One ; 12(3): e0174401, 2017.

Article em En | MEDLINE | ID: mdl-28339485

Assuntos

Artérias Carótidas/efeitos dos fármacos; Hipocampo/efeitos dos fármacos; Hipertensão/metabolismo; Estresse Oxidativo/efeitos dos fármacos; Poli(ADP-Ribose) Polimerase-1/antagonistas & inibidores; Inibidores de Poli(ADP-Ribose) Polimerases/farmacologia; Remodelação Vascular/efeitos dos fármacos; Animais; Pressão Sanguínea/efeitos dos fármacos; Artérias Carótidas/metabolismo; Artérias Carótidas/patologia; Hipocampo/metabolismo; Hipocampo/patologia; Hipertensão/patologia; Masculino; Piperidinas/farmacologia; Quinazolinas/farmacologia; Ratos; Ratos Endogâmicos SHR; Ratos Endogâmicos WKY

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artérias Carótidas / Estresse Oxidativo / Remodelação Vascular / Inibidores de Poli(ADP-Ribose) Polimerases / Poli(ADP-Ribose) Polimerase-1 / Hipocampo / Hipertensão Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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