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Gain in the short arm of chromosome 2 (2p+) induces gene overexpression and drug resistance in chronic lymphocytic leukemia: analysis of the central role of XPO1.
Cosson, A; Chapiro, E; Bougacha, N; Lambert, J; Herbi, L; Cung, H-A; Algrin, C; Keren, B; Damm, F; Gabillaud, C; Brunelle-Navas, M-N; Davi, F; Merle-Béral, H; Le Garff-Tavernier, M; Roos-Weil, D; Choquet, S; Uzunov, M; Morel, V; Leblond, V; Maloum, K; Lepretre, S; Feugier, P; Lesty, C; Lejeune, J; Sutton, L; Landesman, Y; Susin, S A; Nguyen-Khac, F.
Afiliação
  • Cosson A; INSERM UMR_S 1138, Cell Death and Drug Resistance in Lymphoproliferative Disorders Team, Centre de Recherche des Cordeliers, Paris, France.
  • Chapiro E; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1138, Centre de Recherche des Cordeliers, Paris, France.
  • Bougacha N; Université Paris Descartes, Sorbonne Paris Cité, UMR_S 1138, Centre de Recherche des Cordeliers, Paris, France.
  • Lambert J; INSERM UMR_S 1138, Cell Death and Drug Resistance in Lymphoproliferative Disorders Team, Centre de Recherche des Cordeliers, Paris, France.
  • Herbi L; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1138, Centre de Recherche des Cordeliers, Paris, France.
  • Cung HA; Service d'Hématologie Biologique, GH Pitié-Salpêtrière, Paris, France.
  • Algrin C; INSERM UMR_S 1138, Cell Death and Drug Resistance in Lymphoproliferative Disorders Team, Centre de Recherche des Cordeliers, Paris, France.
  • Keren B; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1138, Centre de Recherche des Cordeliers, Paris, France.
  • Damm F; Université Paris Descartes, Sorbonne Paris Cité, UMR_S 1138, Centre de Recherche des Cordeliers, Paris, France.
  • Gabillaud C; Service de Biostatistique et Informatique Médicale, Hôpital Saint Louis, Paris, France.
  • Brunelle-Navas MN; INSERM UMR_S 1138, Cell Death and Drug Resistance in Lymphoproliferative Disorders Team, Centre de Recherche des Cordeliers, Paris, France.
  • Davi F; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1138, Centre de Recherche des Cordeliers, Paris, France.
  • Merle-Béral H; Université Paris Descartes, Sorbonne Paris Cité, UMR_S 1138, Centre de Recherche des Cordeliers, Paris, France.
  • Le Garff-Tavernier M; Service d'Hématologie Biologique, GH Pitié-Salpêtrière, Paris, France.
  • Roos-Weil D; Service d'Hématologie Biologique, GH Pitié-Salpêtrière, Paris, France.
  • Choquet S; Département de génétique, GH Pitié-Salpêtrière, Paris, France.
  • Uzunov M; INSERM U1170, Institut Gustave Roussy, Villejuif, France.
  • Morel V; Service d'Hématologie Biologique, GH Pitié-Salpêtrière, Paris, France.
  • Leblond V; INSERM UMR_S 1138, Cell Death and Drug Resistance in Lymphoproliferative Disorders Team, Centre de Recherche des Cordeliers, Paris, France.
  • Maloum K; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1138, Centre de Recherche des Cordeliers, Paris, France.
  • Lepretre S; Université Paris Descartes, Sorbonne Paris Cité, UMR_S 1138, Centre de Recherche des Cordeliers, Paris, France.
  • Feugier P; INSERM UMR_S 1138, Cell Death and Drug Resistance in Lymphoproliferative Disorders Team, Centre de Recherche des Cordeliers, Paris, France.
  • Lesty C; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1138, Centre de Recherche des Cordeliers, Paris, France.
  • Lejeune J; Service d'Hématologie Biologique, GH Pitié-Salpêtrière, Paris, France.
  • Sutton L; INSERM UMR_S 1138, Cell Death and Drug Resistance in Lymphoproliferative Disorders Team, Centre de Recherche des Cordeliers, Paris, France.
  • Landesman Y; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1138, Centre de Recherche des Cordeliers, Paris, France.
  • Susin SA; Service d'Hématologie Biologique, GH Pitié-Salpêtrière, Paris, France.
  • Nguyen-Khac F; INSERM UMR_S 1138, Cell Death and Drug Resistance in Lymphoproliferative Disorders Team, Centre de Recherche des Cordeliers, Paris, France.
Leukemia ; 31(7): 1625-1629, 2017 07.
Article em En | MEDLINE | ID: mdl-28344316
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triazóis / Cromossomos Humanos Par 2 / Leucemia Linfocítica Crônica de Células B / Regulação Leucêmica da Expressão Gênica / Receptores Citoplasmáticos e Nucleares / Resistencia a Medicamentos Antineoplásicos / Carioferinas / Hidrazinas Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triazóis / Cromossomos Humanos Par 2 / Leucemia Linfocítica Crônica de Células B / Regulação Leucêmica da Expressão Gênica / Receptores Citoplasmáticos e Nucleares / Resistencia a Medicamentos Antineoplásicos / Carioferinas / Hidrazinas Idioma: En Ano de publicação: 2017 Tipo de documento: Article