One-step synthesis of nitrogen, boron co-doped fluorescent carbon nanoparticles for glucose detection.
Luminescence
; 32(6): 1031-1038, 2017 Sep.
Article
em En
| MEDLINE
| ID: mdl-28371213
ABSTRACT
Heteroatom-doped carbon nanoparticles (CNPs) have attracted considerable attention due to an effective improvement in their intrinsic properties. Here, a facile and simple synthesis of nitrogen, boron co-doped carbon nanoparticles (NB-CNPs) from a sole precursor, 3-aminophenylboronic acid, was performed via a one-step solid-phase approach. Because of the presence of boronic acid, NB-CNPs can be used directly as a fluorescent probe for glucose. Based on a boronic acid-triggered specific reaction, we developed a simple NB-CNP probe without surface modification for the detection of glucose. When glucose was introduced, the fluorescence of NB-CNPs was suppressed through a surface-quenching states mechanism. Obvious fluorescence quenching allowed the highly sensitive determination of glucose with a limit of detection of 1.8 µM. Moreover, the proposed method has been successfully used to detect glucose in urine from people with diabetes, suggesting potential application in sensing glucose.
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Base de dados:
MEDLINE
Assunto principal:
Boro
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Técnicas de Química Analítica
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Nanopartículas
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Glucose
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Nitrogênio
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article