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Genetic characterization of orf virus associated with an outbreak of severe orf in goats at a farm in Lusaka, Zambia (2015).
Simulundu, Edgar; Mtine, Nandi; Kapalamula, Thoko F; Kajihara, Masahiro; Qiu, Yongjin; Ngoma, James; Zulu, Victor; Kwenda, Geoffrey; Chisanga, Chrispin; Phiri, Isaac K; Takada, Ayato; Mweene, Aaron S.
Afiliação
  • Simulundu E; Department of Disease Control, School of Veterinary Medicine, University of Zambia, PO Box 32379, Lusaka, Zambia. esikabala@yahoo.com.
  • Mtine N; Department of Biomedical Sciences, School of Health Sciences, University of Zambia, PO Box 50110, Lusaka, Zambia.
  • Kapalamula TF; Department of Disease Control, School of Veterinary Medicine, University of Zambia, PO Box 32379, Lusaka, Zambia.
  • Kajihara M; Division of Global Epidemiology, Hokkaido University Research Center for Zoonosis Control, Sapporo, Japan.
  • Qiu Y; Hokudai Center for Zoonosis Control in Zambia, School of Veterinary Medicine, University of Zambia, PO Box 32379, Lusaka, Zambia.
  • Ngoma J; Department of Clinical Studies, School of Veterinary Medicine, University of Zambia, PO Box 32379, Lusaka, Zambia.
  • Zulu V; Department of Clinical Studies, School of Veterinary Medicine, University of Zambia, PO Box 32379, Lusaka, Zambia.
  • Kwenda G; Department of Biomedical Sciences, School of Health Sciences, University of Zambia, PO Box 50110, Lusaka, Zambia.
  • Chisanga C; Department of Biomedical Sciences, School of Health Sciences, University of Zambia, PO Box 50110, Lusaka, Zambia.
  • Phiri IK; Department of Clinical Studies, School of Veterinary Medicine, University of Zambia, PO Box 32379, Lusaka, Zambia.
  • Takada A; Department of Disease Control, School of Veterinary Medicine, University of Zambia, PO Box 32379, Lusaka, Zambia.
  • Mweene AS; Division of Global Epidemiology, Hokkaido University Research Center for Zoonosis Control, Sapporo, Japan.
Arch Virol ; 162(8): 2363-2367, 2017 Aug.
Article em En | MEDLINE | ID: mdl-28378295
ABSTRACT
Orf or contagious ecthyma is a neglected and economically important zoonotic disease caused by a dermatotropic parapoxvirus that commonly affects domestic small ruminants. Although orf is globally distributed, there is a paucity of information on the disease in many African countries. Here, a suspected severe outbreak of orf in goats at a farm in Lusaka was investigated. Orf virus (ORFV) infection was confirmed by PCR amplification of viral DNA (RNA polymerase, B2L and virus interferon-resistance genes) in clinical samples. Some detected genes were sequenced and phylogenetically analyzed. This is the first report on molecular characterization of ORFV in goats in Zambia.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus do Orf / Doenças das Cabras / Ectima Contagioso Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus do Orf / Doenças das Cabras / Ectima Contagioso Idioma: En Ano de publicação: 2017 Tipo de documento: Article