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Whole-Genome Sequences of Burkholderia pseudomallei Isolates Exhibiting Decreased Meropenem Susceptibility.
Price, Erin P; Smith, Melissa Laird; Paxinos, Ellen E; Tallon, Luke J; Sadzewicz, Lisa; Sengamalay, Naomi; Baird, Robert W; Currie, Bart J; Sarovich, Derek S.
Afiliação
  • Price EP; Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia eprice@usc.edu.au.
  • Smith ML; Centre for Animal Health Innovation, Faculty of Science, Health, Education and Engineering, University of the Sunshine Coast, Sippy Downs, Queensland, Australia.
  • Paxinos EE; Pacific Biosciences, Menlo Park, California, USA.
  • Tallon LJ; Pacific Biosciences, Menlo Park, California, USA.
  • Sadzewicz L; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Sengamalay N; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Baird RW; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Currie BJ; Department of Infectious Diseases and Northern Territory Medical Program, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
  • Sarovich DS; Pathology Department, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
Genome Announc ; 5(14)2017 Apr 06.
Article em En | MEDLINE | ID: mdl-28385830
ABSTRACT
We report here paired isogenic Burkholderia pseudomallei genomes obtained from three patients receiving intravenous meropenem for melioidosis treatment, with post-meropenem isolates developing decreased susceptibility. Two genomes were finished, and four were drafted to improved high-quality standard. These genomes will be used to identify meropenem resistance mechanisms in B. pseudomallei.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article