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Traumatic Abdominal Solid Organ Injury Patients Might Benefit From Thromboelastography-Guided Blood Component Therapy.
Wang, Hao; Robinson, Richard D; Phillips, Jessica L; Ryon, Andrew; Simpson, Scott; Ford, Jonathan R; Umejiego, Johnbosco; Duane, Therese M; Putty, Bradley; Zenarosa, Nestor R.
Afiliação
  • Wang H; Department of Emergency Medicine, Integrative Emergency Services Physician Group, John Peter Smith Health Network, 1500 S. Main St., Fort Worth, TX 76104, USA.
  • Robinson RD; Department of Emergency Medicine, Integrative Emergency Services Physician Group, John Peter Smith Health Network, 1500 S. Main St., Fort Worth, TX 76104, USA.
  • Phillips JL; Research Institute, John Peter Smith Health Network, 1500 S. Main St., Fort Worth, TX 76104, USA.
  • Ryon A; Department of Emergency Medicine, Integrative Emergency Services Physician Group, John Peter Smith Health Network, 1500 S. Main St., Fort Worth, TX 76104, USA.
  • Simpson S; Department of Emergency Medicine, Integrative Emergency Services Physician Group, John Peter Smith Health Network, 1500 S. Main St., Fort Worth, TX 76104, USA.
  • Ford JR; Department of Emergency Medicine, Integrative Emergency Services Physician Group, John Peter Smith Health Network, 1500 S. Main St., Fort Worth, TX 76104, USA.
  • Umejiego J; Research Institute, John Peter Smith Health Network, 1500 S. Main St., Fort Worth, TX 76104, USA.
  • Duane TM; Department of General Surgery, John Peter Smith Health Network, 1500 S. Main St., Fort Worth, TX 76104, USA.
  • Putty B; Department of General Surgery, John Peter Smith Health Network, 1500 S. Main St., Fort Worth, TX 76104, USA.
  • Zenarosa NR; Department of Emergency Medicine, Integrative Emergency Services Physician Group, John Peter Smith Health Network, 1500 S. Main St., Fort Worth, TX 76104, USA.
J Clin Med Res ; 9(5): 433-438, 2017 May.
Article em En | MEDLINE | ID: mdl-28392864
ABSTRACT

BACKGROUND:

Thromboelastography (TEG) has been utilized for the guidance of blood component therapy (BCT). We aimed to investigate the association between emergent TEG-guided BCT and clinical outcomes in patients with traumatic abdominal solid organ (liver and/or spleen) injuries.

METHODS:

A single center retrospective study of patients who sustained traumatic liver and/or spleen injuries receiving emergent BCT was conducted. TEG was ordered in all these patients. Patient demographics, general injury information, outcomes, BCT, and TEG parameters were analyzed and compared in patients receiving TEG-guided BCT versus those without.

RESULTS:

A total of 166 patients were enrolled, of whom 52% (86/166) received TEG-guided BCT. A mortality of 12% was noted among patients with TEG-guided BCT when compared with 19% of mortality in patients with non-TEG-guided BCT (P > 0.05). An average of 4 units of packed red blood cell (PRBC) was received in patients with TEG-guided BCT when compared to an average of 9 units of PRBC received in non-TEG-guided BCT patients (P < 0.01). A longer hospital length of stay (LOS, 19 ± 16 days) was found among non-TEG-guided BCT patients when compared to the TEG-guided BCT group (14 ± 12 days, P < 0.05). TEG-guided BCT showed as an independent factor associated with hospital LOS after other variables were adjusted (coefficiency 5.44, 95% confidence interval 0.69 - 10.18).

CONCLUSIONS:

Traumatic abdominal solid organ injury patients receiving blood transfusions might benefit from TEG-guided BCT as indicated by less blood products needed and less hospitalization stay among the cohort.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article