Electrosteric stealth Rivastigmine loaded liposomes for brain targeting: preparation, characterization, ex vivo, bio-distribution and in vivo pharmacokinetic studies.

Nageeb El-Helaly, Sara; Abd Elbary, Ahmed; Kassem, Mohamed A; El-Nabarawi, Mohamed A

Nageeb El-Helaly, Sara; Abd Elbary, Ahmed; Kassem, Mohamed A; El-Nabarawi, Mohamed A.

Afiliação

Nageeb El-Helaly S; a Department of Pharmaceutics and Industrial Pharmacy , Faculty of Pharmacy, Cairo University , Cairo , Egypt.
Abd Elbary A; a Department of Pharmaceutics and Industrial Pharmacy , Faculty of Pharmacy, Cairo University , Cairo , Egypt.
Kassem MA; a Department of Pharmaceutics and Industrial Pharmacy , Faculty of Pharmacy, Cairo University , Cairo , Egypt.
El-Nabarawi MA; a Department of Pharmaceutics and Industrial Pharmacy , Faculty of Pharmacy, Cairo University , Cairo , Egypt.

Drug Deliv ; 24(1): 692-700, 2017 Nov.

Article em En | MEDLINE | ID: mdl-28415883

Assuntos

Encéfalo; Animais; Lipossomos; Tamanho da Partícula; Fosfatidiletanolaminas; Polietilenoglicóis; Rivastigmina; Ovinos

Palavras-chave

Rivastigmine; Tween 80; ex vivo permeation; in vivo pharmacokinetic studies; pegylated liposomes

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo Idioma: En Ano de publicação: 2017 Tipo de documento: Article