Synthesis, Characterization, Antimicrobial and Antiproliferative Activity Evaluation of Cu(II), Co(II), Zn(II), Ni(II) and Pt(II) Complexes with Isoniazid-Derived Compound.

PahonÈu, Elena; IlieÈ, Diana-Carolina; Shova, Sergiu; Oprean, Camelia; Paunescu, Virgil; Olaru, Octavian Tudorel; Radulescu, Flavian Ètefan; Gulea, Aurelian; RoÈu, Tudor; Draganescu, Doina

PahonÈu, Elena; IlieÈ, Diana-Carolina; Shova, Sergiu; Oprean, Camelia; Paunescu, Virgil; Olaru, Octavian Tudorel; Radulescu, Flavian Ètefan; Gulea, Aurelian; RoÈu, Tudor; Draganescu, Doina.

Afiliação

PahonÈu E; Inorganic Chemistry Department, Faculty of Pharmacy, University of Medicine and Pharmacy "Carol Davila", 6 Traian Vuia Street, 020956 Bucharest, Romania. elenaandmihaela@yahoo.com.
IlieÈ DC; Organic Chemistry Department, Faculty of Pharmacy, University of Medicine and Pharmacy "Carol Davila", 6 Traian Vuia Street, 020956 Bucharest, Romania. ilies_diana@hotmail.com.
Shova S; Institute of Macromolecular Chemistry "Petru Poni", 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania. shova@icmpp.ro.
Oprean C; Environmental and Food Chemistry Department, Faculty of Pharmacy, University of Medicine and Pharmacy "Victor Babes", 2nd Eftimie Murgu Sq., 300041 Timisoara, Romania. camelia.sass5@gmail.com.
Paunescu V; "Pius Brinzeu" TimiÈoara County Emergency Clinical Hospital, Oncogen Institute, 156 Liviu Rebreanu, 300723 Timisoara, Romania. camelia.sass5@gmail.com.
Olaru OT; "Pius Brinzeu" TimiÈoara County Emergency Clinical Hospital, Oncogen Institute, 156 Liviu Rebreanu, 300723 Timisoara, Romania. genostem@yahoo.com.
Radulescu FÈ; Functional Sciences Department, Faculty of Medicine, University of Medicine and Pharmacy "Victor Babes", 2 Eftimie Murgu Square, 300041 Timisoara, Romania. genostem@yahoo.com.
Gulea A; Pharmaceutical Botany and Cell Biology Department, Faculty of Pharmacy, University of Medicine and Pharmacy "Carol Davila", 6 Traian Vuia Street, 020956 Bucharest, Romania. octav_olaru2002@yahoo.com.
RoÈu T; Pharmaceutical Biotechnology Department, Faculty of Pharmacy, University of Medicine and Pharmacy "Carol Davila", 6 Traian Vuia Street, 020956 Bucharest, Romania. flavian_stefan@yahoo.com.
Draganescu D; Coordination Chemistry Department, Moldova State University, 60 Mateevici Street, 2009 Chisinau, Moldova. dociu1946@yahoo.com.

Molecules ; 22(4)2017 Apr 19.

Article em En | MEDLINE | ID: mdl-28422067

Assuntos

Anti-Infecciosos/síntese química; Anti-Infecciosos/farmacologia; Antineoplásicos/síntese química; Antineoplásicos/farmacologia; Isoniazida/síntese química; Isoniazida/farmacologia; Metais/química; Bactérias/efeitos dos fármacos; Linhagem Celular Tumoral; Sobrevivência Celular/efeitos dos fármacos; Cobalto/química; Cobre/química; Fungos/efeitos dos fármacos; Humanos; Isoniazida/análogos & derivados; Testes de Sensibilidade Microbiana; Modelos Moleculares; Estrutura Molecular; Níquel/química; Platina/química; Solubilidade; Análise Espectral/métodos; Zinco/química

Palavras-chave

antimicrobial activity; cobalt(II); copper(II); human breast SKBR-3 and MCF-7; human melanoma A375; lung adenocarcinoma cell NCI-H1573; nickel(II) and platinum(II) complexes; zinc(II)

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Isoniazida / Metais / Anti-Infecciosos / Antineoplásicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google