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PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.
Day, Tovah A; Layer, Jacob V; Cleary, J Patrick; Guha, Srijoy; Stevenson, Kristen E; Tivey, Trevor; Kim, Sunhee; Schinzel, Anna C; Izzo, Francesca; Doench, John; Root, David E; Hahn, William C; Price, Brendan D; Weinstock, David M.
Afiliação
  • Day TA; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
  • Layer JV; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
  • Cleary JP; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
  • Guha S; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
  • Stevenson KE; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
  • Tivey T; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
  • Kim S; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
  • Schinzel AC; Genetic Perturbation Platform, Broad Institute of MIT and Harvard University, 415 Main Street, Cambridge, Massachusetts 02142, USA.
  • Izzo F; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
  • Doench J; Genetic Perturbation Platform, Broad Institute of MIT and Harvard University, 415 Main Street, Cambridge, Massachusetts 02142, USA.
  • Root DE; Genetic Perturbation Platform, Broad Institute of MIT and Harvard University, 415 Main Street, Cambridge, Massachusetts 02142, USA.
  • Hahn WC; Genetic Perturbation Platform, Broad Institute of MIT and Harvard University, 415 Main Street, Cambridge, Massachusetts 02142, USA.
  • Price BD; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
  • Weinstock DM; Genetic Perturbation Platform, Broad Institute of MIT and Harvard University, 415 Main Street, Cambridge, Massachusetts 02142, USA.
Nat Commun ; 8: 15110, 2017 04 27.
Article em En | MEDLINE | ID: mdl-28447610
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Translocação Genética / DNA / Poli(ADP-Ribose) Polimerases / Proteínas de Ciclo Celular / Enzimas Reparadoras do DNA / Enzimas de Conjugação de Ubiquitina / Proteínas de Ligação a DNA / Quadruplex G / Proteína 1 de Ligação à Proteína Supressora de Tumor p53 Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Translocação Genética / DNA / Poli(ADP-Ribose) Polimerases / Proteínas de Ciclo Celular / Enzimas Reparadoras do DNA / Enzimas de Conjugação de Ubiquitina / Proteínas de Ligação a DNA / Quadruplex G / Proteína 1 de Ligação à Proteína Supressora de Tumor p53 Idioma: En Ano de publicação: 2017 Tipo de documento: Article