Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons.

Laidlaw, Stephen M; Marukian, Svetlana; Gilmore, Rachel H; Cashman, Siobhán B; Nechyporuk-Zloy, Volodymyr; Rice, Charles M; Dustin, Lynn B

Laidlaw, Stephen M; Marukian, Svetlana; Gilmore, Rachel H; Cashman, Siobhán B; Nechyporuk-Zloy, Volodymyr; Rice, Charles M; Dustin, Lynn B.

Afiliação

Laidlaw SM; Kennedy Institute of Rheumatology, The University of Oxford, Oxford, United Kingdom; Peter Medawar Building for Pathogen Research, The University of Oxford, Oxford, United Kingdom.
Marukian S; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.
Gilmore RH; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.
Cashman SB; Kennedy Institute of Rheumatology, The University of Oxford, Oxford, United Kingdom; Peter Medawar Building for Pathogen Research, The University of Oxford, Oxford, United Kingdom.
Nechyporuk-Zloy V; Kennedy Institute of Rheumatology, The University of Oxford, Oxford, United Kingdom.
Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.
Dustin LB; Kennedy Institute of Rheumatology, The University of Oxford, Oxford, United Kingdom; Peter Medawar Building for Pathogen Research, The University of Oxford, Oxford, United Kingdom; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York. Electronic address: lynn

Gastroenterology ; 153(2): 566-578.e5, 2017 08.

Article em En | MEDLINE | ID: mdl-28456632

Assuntos

Antivirais/farmacologia; Hepacivirus/efeitos dos fármacos; Hepatite C/tratamento farmacológico; Interferons/farmacologia; Fator de Necrose Tumoral alfa/farmacologia; Carcinoma Hepatocelular/virologia; Linhagem Celular Tumoral; Genótipo; Hepacivirus/genética; Hepatócitos/efeitos dos fármacos; Hepatócitos/virologia; Humanos; Janus Quinases/metabolismo; Fígado/citologia; Neoplasias Hepáticas/virologia; Receptores do Fator de Necrose Tumoral/metabolismo; Replicon/efeitos dos fármacos; Transdução de Sinais/efeitos dos fármacos; Fator de Necrose Tumoral alfa/metabolismo; Replicação Viral/efeitos dos fármacos

Palavras-chave

Immune Regulation; Innate Immunity; Liver Disease; Viral Infection

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Interferons / Fator de Necrose Tumoral alfa / Hepatite C / Hepacivirus Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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