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Recruitment failure and futility were the most common reasons for discontinuation of clinical drug trials. Results of a nationwide inception cohort study in the Netherlands.
van den Bogert, Cornelis A; Souverein, Patrick C; Brekelmans, Cecile T M; Janssen, Susan W J; Koëter, Gerard H; Leufkens, Hubert G M; Bouter, Lex M.
Afiliação
  • van den Bogert CA; Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, P.O. Box 80082, 3584 CG Utrecht, The Netherlands; Central Committee on Research Involving Human Subjects (CCMO),
  • Souverein PC; Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, P.O. Box 80082, 3584 CG Utrecht, The Netherlands. Electronic address: P.C.Souverein@UU.nl.
  • Brekelmans CTM; Central Committee on Research Involving Human Subjects (CCMO), Parnassusplein 5, P.O. Box 16302, 2511 VX The Hague, The Netherlands.
  • Janssen SWJ; Department of Public Health and Health Services, National Institute for Public Health and the Environment (RIVM), Antonie van Leeuwenhoeklaan 9, P.O. Box 13720 BA, Bilthoven 3721 MA, The Netherlands.
  • Koëter GH; Central Committee on Research Involving Human Subjects (CCMO), Parnassusplein 5, P.O. Box 16302, 2511 VX The Hague, The Netherlands.
  • Leufkens HGM; Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, P.O. Box 80082, 3584 CG Utrecht, The Netherlands.
  • Bouter LM; Department of Epidemiology and Biostatistics, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands.
J Clin Epidemiol ; 88: 140-147, 2017 Aug.
Article em En | MEDLINE | ID: mdl-28487159
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Ensaios Clínicos como Assunto / Seleção de Pacientes / Término Precoce de Ensaios Clínicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Ensaios Clínicos como Assunto / Seleção de Pacientes / Término Precoce de Ensaios Clínicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article