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Efficient Recreation of t(11;22) EWSR1-FLI1+ in Human Stem Cells Using CRISPR/Cas9.
Torres-Ruiz, Raul; Martinez-Lage, Marta; Martin, Maria C; Garcia, Aida; Bueno, Clara; Castaño, Julio; Ramirez, Juan C; Menendez, Pablo; Cigudosa, Juan C; Rodriguez-Perales, Sandra.
Afiliação
  • Torres-Ruiz R; Molecular Cytogenetics Group, Human Cancer Genetics Program, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid 28029, Spain; Department of Biomedicine, Josep Carreras Leukemia Research Institute, School of Medicine, University of Barcelona, Barcelona 08036, Spain. Electronic address: rto
  • Martinez-Lage M; Molecular Cytogenetics Group, Human Cancer Genetics Program, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid 28029, Spain.
  • Martin MC; Molecular Cytogenetics Group, Human Cancer Genetics Program, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid 28029, Spain.
  • Garcia A; Hematopoietic Innovative Therapies Division, Centro Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT)-Centro Investigaciones Biomédicas Red Enfermedades Raras (CIBERER), Madrid 28040, Spain.
  • Bueno C; Department of Biomedicine, Josep Carreras Leukemia Research Institute, School of Medicine, University of Barcelona, Barcelona 08036, Spain.
  • Castaño J; Department of Biomedicine, Josep Carreras Leukemia Research Institute, School of Medicine, University of Barcelona, Barcelona 08036, Spain.
  • Ramirez JC; VIVEBioTECH, San Sebastian 20009, Spain.
  • Menendez P; Department of Biomedicine, Josep Carreras Leukemia Research Institute, School of Medicine, University of Barcelona, Barcelona 08036, Spain; Instituciò Catalana de Recerca i Estudis Avançats (ICREA), Passeig Lluis Companys, Barcelona 08010, Spain; Centro de Investigación Biomédica en Red de Cáncer (C
  • Cigudosa JC; Molecular Cytogenetics Group, Human Cancer Genetics Program, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid 28029, Spain.
  • Rodriguez-Perales S; Molecular Cytogenetics Group, Human Cancer Genetics Program, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid 28029, Spain. Electronic address: srodriguezp@cnio.es.
Stem Cell Reports ; 8(5): 1408-1420, 2017 05 09.
Article em En | MEDLINE | ID: mdl-28494941
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing / Translocação Genética / Proteínas de Fusão Oncogênica / Células-Tronco Pluripotentes Induzidas / Sistemas CRISPR-Cas Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing / Translocação Genética / Proteínas de Fusão Oncogênica / Células-Tronco Pluripotentes Induzidas / Sistemas CRISPR-Cas Idioma: En Ano de publicação: 2017 Tipo de documento: Article