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Synthesis and pharmacological evaluation of neurosteroid photoaffinity ligands.
Savechenkov, Pavel Y; Chiara, David C; Desai, Rooma; Stern, Alexander T; Zhou, Xiaojuan; Ziemba, Alexis M; Szabo, Andrea L; Zhang, Yinghui; Cohen, Jonathan B; Forman, Stuart A; Miller, Keith W; Bruzik, Karol S.
Afiliação
  • Savechenkov PY; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 South Wood Street (M/C 781), Chicago, IL 60612-7231, USA.
  • Chiara DC; Department of Neurobiology, 220 Longwood Avenue, Harvard Medical School, Boston, MA 02115, USA.
  • Desai R; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA.
  • Stern AT; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA.
  • Zhou X; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA.
  • Ziemba AM; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA.
  • Szabo AL; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA.
  • Zhang Y; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA.
  • Cohen JB; Department of Neurobiology, 220 Longwood Avenue, Harvard Medical School, Boston, MA 02115, USA.
  • Forman SA; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA.
  • Miller KW; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA; Department of Biological Chemistry and Molecular Pharmacology, 220 Longwood Avenue, Harvard Medical School, Boston, MA 02115, USA.
  • Bruzik KS; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 South Wood Street (M/C 781), Chicago, IL 60612-7231, USA. Electronic address: kbruzik@uic.edu.
Eur J Med Chem ; 136: 334-347, 2017 Aug 18.
Article em En | MEDLINE | ID: mdl-28505538

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pregnanodionas / Receptores de GABA-A Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pregnanodionas / Receptores de GABA-A Idioma: En Ano de publicação: 2017 Tipo de documento: Article