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Phosphorylated Presenilin 1 decreases ß-amyloid by facilitating autophagosome-lysosome fusion.
Bustos, Victor; Pulina, Maria V; Bispo, Ashley; Lam, Alison; Flajolet, Marc; Gorelick, Fred S; Greengard, Paul.
Afiliação
  • Bustos V; Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065; vbustos@rockefeller.edu greengard@rockefeller.edu.
  • Pulina MV; Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065.
  • Bispo A; Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065.
  • Lam A; Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065.
  • Flajolet M; Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065.
  • Gorelick FS; Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520.
  • Greengard P; Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06520.
Proc Natl Acad Sci U S A ; 114(27): 7148-7153, 2017 07 03.
Article em En | MEDLINE | ID: mdl-28533369
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Presenilina-1 / Autofagossomos / Lisossomos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Presenilina-1 / Autofagossomos / Lisossomos Idioma: En Ano de publicação: 2017 Tipo de documento: Article