Thermodynamic framework to assess low abundance DNA mutation detection by hybridization.

Willems, Hanny; Jacobs, An; Hadiwikarta, Wahyu Wijaya; Venken, Tom; Valkenborg, Dirk; Van Roy, Nadine; Vandesompele, Jo; Hooyberghs, Jef

Willems, Hanny; Jacobs, An; Hadiwikarta, Wahyu Wijaya; Venken, Tom; Valkenborg, Dirk; Van Roy, Nadine; Vandesompele, Jo; Hooyberghs, Jef.

Afiliação

Willems H; Flemish Institute for Technological Research, VITO, Mol, Belgium.
Jacobs A; Flemish Institute for Technological Research, VITO, Mol, Belgium.
Hadiwikarta WW; Flemish Institute for Technological Research, VITO, Mol, Belgium.
Venken T; Institute for Theoretical Physics, KULeuven, Leuven, Belgium.
Valkenborg D; Flemish Institute for Technological Research, VITO, Mol, Belgium.
Van Roy N; Flemish Institute for Technological Research, VITO, Mol, Belgium.
Vandesompele J; Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Diepenbeek, Belgium.
Hooyberghs J; Center for Medical Genetics Ghent (CMGG), Ghent University, Ghent, Belgium.

PLoS One ; 12(5): e0177384, 2017.

Article em En | MEDLINE | ID: mdl-28542229

Assuntos

DNA/genética; Hibridização de Ácido Nucleico/genética; Mutação Puntual/genética; Genes ras/genética; Humanos; Inclusão em Parafina/métodos; Patologia Molecular; Termodinâmica; Proteínas ras/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Mutação Puntual / Hibridização de Ácido Nucleico Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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