C-geranylated flavanones from YingDe black tea and their antioxidant and α-glucosidase inhibition activities.
Food Chem
; 235: 227-233, 2017 Nov 15.
Article
em En
| MEDLINE
| ID: mdl-28554631
ABSTRACT
YingDe black tea is produced from crude tea prepared from leaves of Camellia sinensis var. assamica. In this work, we isolated and identified five novel flavanones, namely, amelliaone A-E (1-5), along with seven known compounds 6-12 from the ethanol extract of YingDe black tea. The structures of these five novel phenolic compounds were determined using extensive 1D and 2D nuclear magnetic resonance spectroscopy experiments. The compounds were further evaluated for antioxidant, α-glucosidase inhibitory, and cytotoxic activities. Compound 1 exhibited higher α-glucosidase inhibitory activity with a half-maximum inhibitory concentration value (IC50) of 10.2µM compared with acarbose (18.2µM).
Palavras-chave
(−)-Epicatechin (PubChem CID: 72276); (−)-Gallocatechin gallate (PubChem CID: 199472); Amentoflavone (PubChem CID: 5281600); Apigenin (PubChem CID: 5280443); Camellia var. assamica; Epigallocatechin gallate (PubChem CID: 65064); Flavanone; Gallic acid (PubChem CID: 370); Quercetin (PubChem CID: 5280343); YingDe black tea; α-Glucosidase inhibitory activity
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Camellia sinensis
/
Flavanonas
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Inibidores de Glicosídeo Hidrolases
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article