In Vitro Efficacy of Moxidectin versus Ivermectin against Sarcoptes scabiei.
Antimicrob Agents Chemother
; 61(8)2017 08.
Article
em En
| MEDLINE
| ID: mdl-28559258
ABSTRACT
Moxidectin is under consideration for development as a treatment for human scabies. As some arthropods show decreased sensitivity to moxidectin relative to ivermectin, it was important to assess this for Sarcoptes scabieiIn vitro assays showed that the concentration of moxidectin required to kill 50% of mites was lower than that of ivermectin (0.5 µM versus 1.8 µM at 24 h; P < 0.0001). This finding provides further support for moxidectin as a candidate for the treatment of human scabies.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sarcoptes scabiei
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Escabiose
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Ivermectina
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Macrolídeos
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Acaricidas
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article