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Engineered Cpf1 variants with altered PAM specificities.
Gao, Linyi; Cox, David B T; Yan, Winston X; Manteiga, John C; Schneider, Martin W; Yamano, Takashi; Nishimasu, Hiroshi; Nureki, Osamu; Crosetto, Nicola; Zhang, Feng.
Afiliação
  • Gao L; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Cox DBT; Department of Biological Engineering, Massachusetts Institute of Technology Cambridge, Massachusetts, USA.
  • Yan WX; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Manteiga JC; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
  • Schneider MW; Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Boston, Massachusetts, USA.
  • Yamano T; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Nishimasu H; Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Boston, Massachusetts, USA.
  • Nureki O; Graduate Program in Biophysics, Harvard Medical School, Boston, Massachusetts, USA.
  • Crosetto N; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
  • Zhang F; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Nat Biotechnol ; 35(8): 789-792, 2017 Aug.
Article em En | MEDLINE | ID: mdl-28581492
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Variação Genética / Engenharia Genética / Mutagênese Sítio-Dirigida / Endonucleases Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Variação Genética / Engenharia Genética / Mutagênese Sítio-Dirigida / Endonucleases Idioma: En Ano de publicação: 2017 Tipo de documento: Article