The contribution of homology arms to nuclease-assisted genome engineering.

Baker, Oliver; Tsurkan, Sarah; Fu, Jun; Klink, Barbara; Rump, Andreas; Obst, Mandy; Kranz, Andrea; Schröck, Evelin; Anastassiadis, Konstantinos; Stewart, A Francis

Baker, Oliver; Tsurkan, Sarah; Fu, Jun; Klink, Barbara; Rump, Andreas; Obst, Mandy; Kranz, Andrea; Schröck, Evelin; Anastassiadis, Konstantinos; Stewart, A Francis.

Afiliação

Baker O; Stem Cell Engineering, Biotechnology Center, Technische Universität Dresden, BioInnovationsZentrum, Tatzberg 47, Dresden 01307, Germany.
Tsurkan S; Genomics, Biotechnology Center, Technische Universität Dresden, BioInnovationsZentrum, Tatzberg 47, Dresden 01307, Germany.
Fu J; Genomics, Biotechnology Center, Technische Universität Dresden, BioInnovationsZentrum, Tatzberg 47, Dresden 01307, Germany.
Klink B; Genomics, Biotechnology Center, Technische Universität Dresden, BioInnovationsZentrum, Tatzberg 47, Dresden 01307, Germany.
Rump A; Shandong University-Helmholtz Joint Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Shanda Nanlu 27, 250100 Jinan, People's Republic of China.
Obst M; Institute for Clinical Genetics, Faculty of Medicine, Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, Dresden 01307, Germany.
Kranz A; Institute for Clinical Genetics, Faculty of Medicine, Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, Dresden 01307, Germany.
Schröck E; Stem Cell Engineering, Biotechnology Center, Technische Universität Dresden, BioInnovationsZentrum, Tatzberg 47, Dresden 01307, Germany.
Anastassiadis K; Genomics, Biotechnology Center, Technische Universität Dresden, BioInnovationsZentrum, Tatzberg 47, Dresden 01307, Germany.
Stewart AF; Genomics, Biotechnology Center, Technische Universität Dresden, BioInnovationsZentrum, Tatzberg 47, Dresden 01307, Germany.

Nucleic Acids Res ; 45(13): 8105-8115, 2017 Jul 27.

Article em En | MEDLINE | ID: mdl-28582546

Assuntos

Sistemas CRISPR-Cas; Engenharia Genética/métodos; Animais; Cromossomos Artificiais Bacterianos/genética; Proteínas de Ligação a DNA/genética; Células-Tronco Embrionárias/metabolismo; Endonucleases/metabolismo; Marcação de Genes; Histona-Lisina N-Metiltransferase; Humanos; Hibridização Genética; Hipoxantina Fosforribosiltransferase/genética; Camundongos; Mutação; Proteína de Leucina Linfoide-Mieloide/genética; Proteínas de Neoplasias/genética

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Engenharia Genética / Sistemas CRISPR-Cas Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Engenharia Genética / Sistemas CRISPR-Cas Idioma: En Ano de publicação: 2017 Tipo de documento: Article