Protein kinase A-mediated phosphorylation of the Broad-Complex transcription factor in silkworm suppresses its transcriptional activity.

Qian, Wenliang; Gang, Xiaoxu; Zhang, Tianlei; Wei, Ling; Yang, Xinxin; Li, Zheng; Yang, Yan; Song, Liang; Wang, Peng; Peng, Jian; Cheng, Daojun; Xia, Qingyou

Qian, Wenliang; Gang, Xiaoxu; Zhang, Tianlei; Wei, Ling; Yang, Xinxin; Li, Zheng; Yang, Yan; Song, Liang; Wang, Peng; Peng, Jian; Cheng, Daojun; Xia, Qingyou.

Afiliação

Qian W; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China.
Gang X; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China.
Zhang T; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China.
Wei L; School of Life Science, Southwest University, Chongqing 400715, China.
Yang X; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China.
Li Z; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China.
Yang Y; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China.
Song L; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China.
Wang P; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China.
Peng J; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China.
Cheng D; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China. Electronic address: chengdj@swu.edu.cn.
Xia Q; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China. Electronic address: xiaqy@swu.edu.cn.

J Biol Chem ; 292(30): 12460-12470, 2017 07 28.

Article em En | MEDLINE | ID: mdl-28584058

Assuntos

Proteínas Quinases Dependentes de AMP Cíclico/metabolismo; Regulação para Baixo; Fatores de Transcrição/antagonistas & inibidores; Fatores de Transcrição/metabolismo; Transcrição Gênica; Animais; Bombyx; Cromatografia Líquida; Proteínas Quinases Dependentes de AMP Cíclico/isolamento & purificação; Fosforilação; Espectrometria de Massas em Tandem; Fatores de Transcrição/química; Fatores de Transcrição/genética

Palavras-chave

20-hydroxyecdysone; Broad-Complex; gene transcription; phosphorylation; post-translational modification (PTM); protein kinase A (PKA); signal transduction; suppression

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Transcrição Gênica / Regulação para Baixo / Proteínas Quinases Dependentes de AMP Cíclico Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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